C Which signaling pathway mediates GGF-induced Schwann cell proliferation? (Ras/Raf/Erk vs. P13-kinase) Maurel, P and JL Salzer (2000) Axonal regulation of Schwann cell proliferation and survival and the initial events of myelination requires Pl 3-kinase activity. J. Neurosci 15:4635 B 25 BrdU index (%) 20- 15 10- 5- p-Akt p-Erk Ctrl Fk GGF LY2.5 LY5 LY10 LY20 Ctrl Fk GGF U1 U2.5 U5 U10 LY294002: P13-kinase inhibitor U0126: Mek Inhibitor

C Which signaling pathway mediates GGF-induced Schwann cell proliferation? (Ras/Raf/Erk vs. P13-kinase) Maurel, P and JL Salzer (2000) Axonal regulation of Schwann cell proliferation and survival and the initial events of myelination requires Pl 3-kinase activity. J. Neurosci 15:4635 B 25 BrdU index (%) 20- 15 10- 5- p-Akt p-Erk Ctrl Fk GGF LY2.5 LY5 LY10 LY20 Ctrl Fk GGF U1 U2.5 U5 U10 LY294002: P13-kinase inhibitor U0126: Mek Inhibitor

Biology: The Dynamic Science (MindTap Course List)

4th Edition

ISBN:9781305389892

Author:Peter J. Russell, Paul E. Hertz, Beverly McMillan

Publisher:Peter J. Russell, Paul E. Hertz, Beverly McMillan

Chapter9: Cell Communication

Section: Chapter Questions

Problem 9TYK

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