Chapter 18, Problem 34QP

Interpretation Introduction

Interpretation:

The feasibility of the dimerization of protein at ${25}^{\circ }\text{C}$ is to be predicted, a comment is to be statedon the effect of the lowering of the temperature, and the reason for the statement,“Why some enzymes lose their activities under cold conditions” is to be explained.

Concept introduction:

The spontaneity of areaction is determined by Gibbs free energy. The mathematical equation is expressed as follows:

$\Delta G=\Delta H-T\Delta S$

Here, $\Delta G$ is Gibbs free energy, $\Delta H$ is the enthalpy of the reaction, $T$ is temperature, and $\Delta S$ is entropy.

$\Delta G$ can predict the spontaneity of areaction as follows:

If $\Delta G<\text{0}$, the system is spontaneous in the forward direction.

If $\Delta G=\text{0}$, the system is in equilibrium.

If $\Delta G>\text{0}$, the system is non-spontaneous in the forward direction.