A synthesis has to be proposed for cyclomethycaine from 4-hydroxybenzoic acid and 2-methylpiperidine. Concept introduction: Esterification reaction: In an esterification reaction, carboxylic acid combines with an alcohol in presence of little concentrated sulphuric acid to produce an ester. Esters reacts with ammonia to form amides. Acid chlorides are most often prepared by treating a carboxylic acid with thionyl chloride. L i A l H 4 is a powerful reducing agent which reduces carboxylic acids to primary alcohol.

Question

show any electrophilic aromatic substitution, identify the electriphile, nucleophile and transition state

Answer 1

Question

Definition Definition Class of organic compounds that contain a carboxyl group ( - COOH ) and has a general formula R - COOH or R - CO 2 H , where R refers to the alkyl, alkenyl, aryl, or other groups. They can undergo different chemical reactions, such as acid-base reactions, esterification, and oxidation. These are essential components of living organisms, playing important roles in metabolic processes, signaling, and as pharmaceuticals.

Chapter 18, Problem 18.53P

Interpretation Introduction

Interpretation:

A synthesis has to be proposed for cyclomethycaine from 4-hydroxybenzoic acid and 2-methylpiperidine.

Concept introduction:

Esterification reaction:

In an esterification reaction, carboxylic acid combines with an alcohol in presence of little concentrated sulphuric acid to produce an ester.

Esters reacts with ammonia to form amides.

Acid chlorides are most often prepared by treating a carboxylic acid with thionyl chloride.

LiAlH4 is a powerful reducing agent which reduces carboxylic acids to primary alcohol.

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Answer 2

Question

Definition Definition Class of organic compounds that contain a carboxyl group ( - COOH ) and has a general formula R - COOH or R - CO 2 H , where R refers to the alkyl, alkenyl, aryl, or other groups. They can undergo different chemical reactions, such as acid-base reactions, esterification, and oxidation. These are essential components of living organisms, playing important roles in metabolic processes, signaling, and as pharmaceuticals.

Chapter 18, Problem 18.53P

Interpretation Introduction

Interpretation:

A synthesis has to be proposed for cyclomethycaine from 4-hydroxybenzoic acid and 2-methylpiperidine.

Concept introduction:

Esterification reaction:

In an esterification reaction, carboxylic acid combines with an alcohol in presence of little concentrated sulphuric acid to produce an ester.

Esters reacts with ammonia to form amides.

Acid chlorides are most often prepared by treating a carboxylic acid with thionyl chloride.

LiAlH4 is a powerful reducing agent which reduces carboxylic acids to primary alcohol.

Expert Solution & Answer

Trending nowThis is a popular solution!

See solution

Check out sample textbook solution

Answer 3

Question

Definition Definition Class of organic compounds that contain a carboxyl group ( - COOH ) and has a general formula R - COOH or R - CO 2 H , where R refers to the alkyl, alkenyl, aryl, or other groups. They can undergo different chemical reactions, such as acid-base reactions, esterification, and oxidation. These are essential components of living organisms, playing important roles in metabolic processes, signaling, and as pharmaceuticals.

Chapter 18, Problem 18.53P

Interpretation Introduction

Interpretation:

A synthesis has to be proposed for cyclomethycaine from 4-hydroxybenzoic acid and 2-methylpiperidine.

Concept introduction:

Esterification reaction:

In an esterification reaction, carboxylic acid combines with an alcohol in presence of little concentrated sulphuric acid to produce an ester.

Esters reacts with ammonia to form amides.

Acid chlorides are most often prepared by treating a carboxylic acid with thionyl chloride.

LiAlH4 is a powerful reducing agent which reduces carboxylic acids to primary alcohol.

Expert Solution & Answer

Trending nowThis is a popular solution!

See solution

Check out sample textbook solution

Answer 4

Question

Definition Definition Class of organic compounds that contain a carboxyl group ( - COOH ) and has a general formula R - COOH or R - CO 2 H , where R refers to the alkyl, alkenyl, aryl, or other groups. They can undergo different chemical reactions, such as acid-base reactions, esterification, and oxidation. These are essential components of living organisms, playing important roles in metabolic processes, signaling, and as pharmaceuticals.

Chapter 18, Problem 18.53P

Interpretation Introduction