Organic Chemistry
8th Edition
ISBN: 9781305580350
Author: William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote
Publisher: Cengage Learning
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Question
Chapter 18.4, Problem 18.4P
(a)
Interpretation Introduction
Interpretation:
The complete equation for the hydrolysis of the given amide in concentrated aqueous
Concept introduction:
Amide hydrolysis in aqueous base:
A carboxylate salt and ammonia or an
For each mole of amide, one mole of base is required.
(b)
Interpretation Introduction
Interpretation:
The complete equation for the hydrolysis of the given amide in concentrated aqueous
Concept introduction:
Amide hydrolysis in aqueous base:
A carboxylate salt and ammonia or an amine will be the product of amide hydrolysis in aqueous base.
For each mole of amide, one mole of base is required.
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Complete equations for the hydrolysis of the amides in Example 18.4 in concentrated aqueous NaOH. Show all products as they exist in aqueous NaOH and the number of moles of NaOH required for hydrolysis of each amide.
b) Compounds in which the –OH of the carboxyl group is replaced by certain other
groups are called carboxylic acid derivatives. The most important of which are
acyl halides, acid anhydrides, esters and amides. Discuss the relationship between
carboxylic acid, acid chloride and acid anhydride
Name (by the common system of nomenclature) the amine (or ammonia) that is formed by the basic hydrolysis of the following acid amide:
Chapter 18 Solutions
Organic Chemistry
Ch. 18.1 - Prob. 18.1PCh. 18.2 - Prob. 18.2PCh. 18.4 - Prob. 18.3PCh. 18.4 - Prob. 18.4PCh. 18.4 - Synthesis of nitriles by nucleophilic displacement...Ch. 18.5 - Complete the following transesterification...Ch. 18.6 - Complete and balance equations for the following...Ch. 18.8 - Prob. AQCh. 18.8 - Several compounds have been found to inhibit...Ch. 18.8 - Prob. CQ
Ch. 18.8 - The following sequence of steps is used to create...Ch. 18.9 - Prob. 18.8PCh. 18.9 - Prob. 18.9PCh. 18.10 - Prob. 18.10PCh. 18.10 - Show how to convert (R)-2-phenylpropanoic acid to...Ch. 18 - Prob. 18.12PCh. 18 - Write the IUPAC name for each compound. (a)...Ch. 18 - Prob. 18.14PCh. 18 - Prob. 18.15PCh. 18 - Propose a structural formula for compound A,...Ch. 18 - Propose a structural formula for compound B,...Ch. 18 - Propose a structural formula for each compound...Ch. 18 - Draw a structural formula for the principal...Ch. 18 - Prob. 18.20PCh. 18 - Prob. 18.21PCh. 18 - Prob. 18.22PCh. 18 - Prob. 18.23PCh. 18 - Prob. 18.24PCh. 18 - Show the product expected when the following...Ch. 18 - The reagent diisobutylaluminum hydride (DIBALH)...Ch. 18 - Prob. 18.27PCh. 18 - Prob. 18.28PCh. 18 - Prob. 18.29PCh. 18 - Nicotinic acid, more commonly named niacin, is one...Ch. 18 - Prob. 18.31PCh. 18 - Prob. 18.32PCh. 18 - Prob. 18.33PCh. 18 - Prob. 18.34PCh. 18 - Prob. 18.35PCh. 18 - Isoniazid, a drug used to treat tuberculosis, is...Ch. 18 - Prob. 18.37PCh. 18 - A step in a synthesis of PGE1 (prostaglandin E1,...Ch. 18 - Prob. 18.39PCh. 18 - Prob. 18.40PCh. 18 - Show how to synthesize 5-nonanone from...Ch. 18 - Prob. 18.42PCh. 18 - The following sequence of steps converts...Ch. 18 - Prob. 18.44PCh. 18 - Prob. 18.45PCh. 18 - Prob. 18.46PCh. 18 - Prob. 18.47PCh. 18 - Following is a retrosynthetic analysis for the...Ch. 18 - Prob. 18.50PCh. 18 - Given this retrosynthetic analysis, propose a...Ch. 18 - Prob. 18.52PCh. 18 - Prob. 18.53PCh. 18 - Prob. 18.54PCh. 18 - In Problem 7.28, we saw this step in Johnsons...Ch. 18 - Prob. 18.56PCh. 18 - Prob. 18.57PCh. 18 - Prob. 18.58PCh. 18 - Prob. 18.59PCh. 18 - Prob. 18.60PCh. 18 - Prob. 18.61PCh. 18 - Prob. 18.62PCh. 18 - Using your reaction roadmap as a guide, show how...Ch. 18 - Using your reaction roadmap as a guide, show how...Ch. 18 - Using your reaction roadmap as a guide, show how...Ch. 18 - Using your reaction roadmap as a guide, show how...Ch. 18 - Minoxidil is a molecule that causes hair growth in...Ch. 18 - Prob. 18.69PCh. 18 - Prob. 18.70PCh. 18 - Prob. 18.71P
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- 8 (Chemical Connections 19C) Once it has been opened, and particularly if it has been left open to the air, a bottle of aspirin may develop a vinegar-like odor. Explain how this might happen.arrow_forwardWrite equations for the hydrolysis of these amides in concentrated aqueous HCl. Show all products as they exist in aqueous HCl and the number of moles of HCl required for hydrolysis of each amidearrow_forwardDraw the structures of the products when each of the following amides undergo hydrolysis with NaOH. You may want to reference (Page) Section 18.6 while completing this problem. ▼ CH3 0 CH,—CH,—CH—C—NH, Draw the molecules on the canvas by choosing buttons from the Tools (for bonds and charg www NN [1] Submit Part B Request Answer H 120 EXP CONT + Marvin JS by ChemAxon • & H H 120 EXP CONT C N O S CI Br - PFL O CH₂ CH3 CH3-CH₂-CH₂-C-N-CH₂-CH3 Draw the molecules on the canvas by choosing buttons from the Tools (for bonds and charg Р H C Z Oarrow_forward
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