A reaction mechanism for the given reaction has to be proposed.

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Several sulfonylureas, a class of compounds containing RSO2NHCONHR, are useful drugs as orally active replacements for injected insulin in patients with adult-onset diabetes. These drugs decrease blood glucose concentrations by stimulating b cells of the pancreas to release insulin and by increasing the sensitivity of insulin receptors in peripheral tissues to insulin stimulation. Tolbutamide is synthesized by the reaction of the sodium salt of p-toluenesulfonamide and ethyl N-butylcarbamate . Propose a mechanism for this step.

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Question

Chapter 18, Problem 18.45P

Interpretation Introduction

Interpretation:

A reaction mechanism for the given reaction has to be proposed.

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