The function of the enzyme ACC1 and its regulation. Introduction: The process of fatty acid synthesis occurs in two steps, that is, by the synthesis of palmitate in sequential addition from growing fatty acyl chain, and by the formation of the compound malonyl-CoA with help ofACC1 enzyme. ACC1, or acetyl-CoA carboxylase 1, is a biotin-dependent enzymethat catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which acts as the substrate for fatty acid synthesis.

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Definition Definition Chemical process in which one or more monomers combine to produce a very large chain-like molecule called a polymer. The functional groups present on the monomers and their steric effects are responsible for polymerization through a sequence of reactions that vary in complexity. There exists a stable covalent chemical bond between monomers that sets apart polymerization from other processes.

Chapter 12, Problem 60SA

Summary Introduction

To review:

The function of the enzyme ACC1 and its regulation.

Introduction:

The process of fatty acid synthesis occurs in two steps, that is, by the synthesis of palmitate in sequential addition from growing fatty acyl chain, and by the formation of the compound malonyl-CoA with help ofACC1 enzyme. ACC1, or acetyl-CoA carboxylase 1, is a biotin-dependent enzymethat catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which acts as the substrate for fatty acid synthesis.

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The carbon-nitrogen peptide bond is rigid, but rotation can take place about the bond between the nitrogen and a-carbon atoms and the bond between the a-carbon and the carbonyl carbon atom. These bond angles define the conformation of the peptide chain. Consider the Ramachandran plot shown to answer both questions. fr (degrees) 180 120 8280 60 ° -60 Which observation most likely describes part of an observed a helix? p=-59 degrees; y = +150 degrees; many Ser residues qp=-140 degrees; w +130 degrees; many Val residues qp=-57 degrees; y = -47 degrees; many Pro residues qp=-60 degrees; y = -47 degrees; many Ala residues p = +60 degrees; y = +40 degrees; many Gly residues Which observations would not likely occur in a ẞ sheet? qp=-59 degrees; y = -49 degrees; many Ala residues qp = +60 degrees; w = +60 degrees; many Gly residues qp=-120 degrees; y = +120 degrees; many Tyr residues ☐ ☐ qp=-139 degrees; y = +135 degrees; many Val residues op=-51 degrees; w+153 degrees; many Gly and Pro…

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A protein biochemist attempted to determine the amino acid sequence of a decapeptide. The results from the trypsin, chymotrypsin, and cyanogen bromide treatments are shown: ⚫ Trypsin digestion gave two fragments with multiple residues (not in order): • T1: Ala, Arg, Phe, Gly, Thr, Trp, Tyr o T2: Lys, Met, Val Chymotrypsin digestion gave four fragments with multiple residues (not in order): • CT1: Ala, Phe • CT2: Thr, Trp • CT3: Lys, Met, Tyr, Val 。 CT4: Arg, Gly ⚫ Treatment with cyanogen bromide yielded a single amino acid, methionine, and a nonapeptide. What is a possible sequence of the decapeptide? Use three-letter abbreviations in your answer, and add a dash between each residue.

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Definition Definition Chemical process in which one or more monomers combine to produce a very large chain-like molecule called a polymer. The functional groups present on the monomers and their steric effects are responsible for polymerization through a sequence of reactions that vary in complexity. There exists a stable covalent chemical bond between monomers that sets apart polymerization from other processes.

Chapter 12, Problem 60SA

Summary Introduction

To review:

The function of the enzyme ACC1 and its regulation.

Introduction:

The process of fatty acid synthesis occurs in two steps, that is, by the synthesis of palmitate in sequential addition from growing fatty acyl chain, and by the formation of the compound malonyl-CoA with help ofACC1 enzyme. ACC1, or acetyl-CoA carboxylase 1, is a biotin-dependent enzymethat catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which acts as the substrate for fatty acid synthesis.

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Answer 3

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Definition Definition Chemical process in which one or more monomers combine to produce a very large chain-like molecule called a polymer. The functional groups present on the monomers and their steric effects are responsible for polymerization through a sequence of reactions that vary in complexity. There exists a stable covalent chemical bond between monomers that sets apart polymerization from other processes.

Chapter 12, Problem 60SA

Summary Introduction

To review:

The function of the enzyme ACC1 and its regulation.

Introduction:

The process of fatty acid synthesis occurs in two steps, that is, by the synthesis of palmitate in sequential addition from growing fatty acyl chain, and by the formation of the compound malonyl-CoA with help ofACC1 enzyme. ACC1, or acetyl-CoA carboxylase 1, is a biotin-dependent enzymethat catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which acts as the substrate for fatty acid synthesis.

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Answer 4

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Definition Definition Chemical process in which one or more monomers combine to produce a very large chain-like molecule called a polymer. The functional groups present on the monomers and their steric effects are responsible for polymerization through a sequence of reactions that vary in complexity. There exists a stable covalent chemical bond between monomers that sets apart polymerization from other processes.

Chapter 12, Problem 60SA

Summary Introduction