Biochemistry: The Molecular Basis of Life
Biochemistry: The Molecular Basis of Life
6th Edition
ISBN: 9780190209896
Author: Trudy McKee, James R. McKee
Publisher: Oxford University Press
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Chapter 12, Problem 2Q
Summary Introduction

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The way MCAD (medium-chain acyl CoenzymeA dehydrogenase)-deficient patients can treat their symptoms considering the glycogen in the liver depletes quickly in children.

Introduction:

MCAD is an enzyme present in the mitochondria that is involved in the catalysis of the first reaction of beta-oxidation. If the MCAD synthesizing gene is mutated, it can lead to MCAD deficiencies, which has the following symptoms; vomiting, fatigue, and hyperglycemia that are accentuated if a personfasts. The substrate of the MCAD enzyme is acyl Coenzyme A. If the MCAD enzyme is not synthesized, this substrate accumulates and depresses gluconeogenesis.

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Biochemistry: The Molecular Basis of Life

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