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Uptake in presence of Na+ Uptake in absence of Na+ Substrate Vmax K+(mM) Vmax K†(mM) L-Leucine 420 0.24 23 0.2 D-Leucine 310 4.7 5 4.7 L-Valine 225 0.31 19 0.31

Uptake in presence of Na+ Uptake in absence of Na+ Substrate Vmax K+(mM) Vmax K†(mM) L-Leucine 420 0.24 23 0.2 D-Leucine 310 4.7 5 4.7 L-Valine 225 0.31 19 0.31

Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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You are studying the uptake of L-leucine by epithelial cells of the mouse intestine. Measurements of the rates of uptake of L-leucine and several
of its analogs, with and without Na+ in the assay buffer, yield the results given in the table below. What can you conclude about the properties and mechanism of the leucine transporter? Would you expect L-leucine uptake to be inhibited by ouabain?

Uptake in presence of Na+ Uptake in absence of Na+ Substrate Vmax K+(mM) Vmax K†(mM) L-Leucine 420 0.24 23 0.2 D-Leucine 310 4.7 5 4.7 L-Valine 225 0.31 19 0.31
Transcribed Image Text:Uptake in presence of Na+ Uptake in absence of Na+ Substrate Vmax K+(mM) Vmax K†(mM) L-Leucine 420 0.24 23 0.2 D-Leucine 310 4.7 5 4.7 L-Valine 225 0.31 19 0.31
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