Select the best explanation of the unfolded protein response (UPR):O A. The UPR senses misfolded proteins through detection of proteins tagged with polyubiquitin chains and sends them for degradation in the lysosomeB. The UPR senses misfolded proteins through recognition of specific oligosaccharide conformations and sends them for degradation via theproteasomeC. The UPR senses high levels of misfolded proteins in the ER and activates ubiquitin ligases to add ubiquitin to the misfolded proteins and target themfor secretion from the cell.D. The UPR senses ER stress in the form of high levels of misfolded proteins and signals the cell to halt translation and induces expression of ERchaperones

When the protein is completely formed it is folded accordingly yo form a biologically active protein…

Select the best explanation of the unfolded protein response (UPR): O A. The UPR senses misfolded proteins through detection of proteins tagged with polyubiquitin chains and sends them for degradation in the lysosome O B. The UPR senses misfolded proteins through recognition of specific oligosaccharide conformations and sends them for degradation via the proteasome OC. The UPR senses high levels of misfolded proteins in the ER and activates ubiquitin ligases to add ubiquitin to the misfolded proteins and target them for secretion from the cell. O D. The UPR senses ER stress in the form of high levels of misfolded proteins and signals the cell to halt translation and induces expression of ER chaperones

Select the best explanation of the unfolded protein response (UPR): O A. The UPR senses misfolded proteins through detection of proteins tagged with polyubiquitin chains and sends them for degradation in the lysosome O B. The UPR senses misfolded proteins through recognition of specific oligosaccharide conformations and sends them for degradation via the proteasome OC. The UPR senses high levels of misfolded proteins in the ER and activates ubiquitin ligases to add ubiquitin to the misfolded proteins and target them for secretion from the cell. O D. The UPR senses ER stress in the form of high levels of misfolded proteins and signals the cell to halt translation and induces expression of ER chaperones

Human Anatomy & Physiology (11th Edition)

11th Edition

ISBN:9780134580999

Author:Elaine N. Marieb, Katja N. Hoehn

Publisher:Elaine N. Marieb, Katja N. Hoehn

Chapter1: The Human Body: An Orientation

Section: Chapter Questions

Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...

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