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Trace the pathway of a protein from translation to the plasma membrane. You may name this protein anything you want, but it must be a transmembrane protein (either single- bass integral membrane protein, or multipass channel protein), with the N-terminus on the cytosolic side of the plasma membrane. The protein must also have several protein nodifications, including (but not limited to) N-linked glycosylation, cysteine disulfide bonds, lipid modifications, and 3-D folding. You do not need to describe the processes of transcription or translation. Assume that transcription has already occurred, and translation has begun, with the mRNA attached to the ibosome. You do, however, need to describe the process(es) by which the protein is modified and transported to the plasma membrane. Any accessory molecules encountered by your protein along the way must be returned to their starting point or conformation.

Trace the pathway of a protein from translation to the plasma membrane. You may name this protein anything you want, but it must be a transmembrane protein (either single- bass integral membrane protein, or multipass channel protein), with the N-terminus on the cytosolic side of the plasma membrane. The protein must also have several protein nodifications, including (but not limited to) N-linked glycosylation, cysteine disulfide bonds, lipid modifications, and 3-D folding. You do not need to describe the processes of transcription or translation. Assume that transcription has already occurred, and translation has begun, with the mRNA attached to the ibosome. You do, however, need to describe the process(es) by which the protein is modified and transported to the plasma membrane. Any accessory molecules encountered by your protein along the way must be returned to their starting point or conformation.

Biochemistry
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
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Trace the pathway of a protein from translation to the plasma membrane. You may name this protein anything you want, but it must be a transmembrane protein (either single- pass integral membrane protein, or multipass channel protein), with the N-terminus on the cytosolic side of the plasma membrane. The protein must also have several protein modifications, including (but not limited to) N-linked glycosylation, cysteine disulfide bonds, lipid modifications, and 3-D folding. You do not need to describe the processes of transcription or translation. Assume that transcription has already occurred, and translation has begun, with the mRNA attached to the ribosome. You do, however, need to describe the process(es) by which the protein is modified and transported to the plasma membrane. Any accessory molecules encountered by your protein along the way must be returned to their starting point or conformation.
Transcribed Image Text:Trace the pathway of a protein from translation to the plasma membrane. You may name this protein anything you want, but it must be a transmembrane protein (either single- pass integral membrane protein, or multipass channel protein), with the N-terminus on the cytosolic side of the plasma membrane. The protein must also have several protein modifications, including (but not limited to) N-linked glycosylation, cysteine disulfide bonds, lipid modifications, and 3-D folding. You do not need to describe the processes of transcription or translation. Assume that transcription has already occurred, and translation has begun, with the mRNA attached to the ribosome. You do, however, need to describe the process(es) by which the protein is modified and transported to the plasma membrane. Any accessory molecules encountered by your protein along the way must be returned to their starting point or conformation.
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