Metabolic syndrome is a clustering of various conditions including high blood pressure, high blood sugar, excess body fat, high serum triglycerides, and low high-density lipoproteins. Scientists studying metabolic syndrome cultured fibroblast cells from a metabolic syndrome patient and

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Metabolic syndrome is a clustering of various conditions including high blood pressure, high blood sugar, excess body fat, high serum triglycerides, and low high-density lipoproteins. Scientists studying metabolic syndrome cultured fibroblast cells from a metabolic syndrome patient and a healthy volunteer and challenged the cells to 100 nM insulin. Ten minutes after the stimulus was applied, they used a protein immunoblot to measure the amount of phosphorylated insulin receptor in the cultures.

 

Use the passage to answer the question.

Insulin, in addition to regulating blood glucose, also promotes satiety. Ghrelin, on the other hand, is a peptide hormone that promotes hunger. Which statement BEST predicts the effect of ghrelin release on the insulin receptor?

  •  
    A.

    It increases insulin receptor expression.

  •  
    B.

    It decreases insulin receptor expression.

  •  
    C.

    It increases insulin receptor phosphorylation.

  •  
    D.

    It decreases insulin receptor phosphorylation.

Insulin (NM)
Insulin Receptor
Phosphorylated
Insulin Receptor
Healthy
0
Metabolic
Syndrome
100
100 0
Transcribed Image Text:Insulin (NM) Insulin Receptor Phosphorylated Insulin Receptor Healthy 0 Metabolic Syndrome 100 100 0
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