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HDL-R: HDLS carry cholesterol to the liver for elimination. Liver cells respond to estrogen to express a protein receptor for HDLS coded by the HDL-R gene (HDL-R gene contains an estrogen response element.) PFK: codes for an enzyme called phosphofructokinase that is used in the first steps of breaking down glucose for energy in all cells. (Gene has no estrogen response element.) CD3: codes for a cell surface protein produced by immune B cells (Gene has no estrogen response element) MRNA transcripts can be collected from cells, made to glow with a fluorescent dye, and added to a microarray chip containing spots with DNA sequences from each of these genes. (In the depiction of the microarrays below o indicates no binding of the mRNA, and • indicates binding.) HDL-R PFK CD3 A B

HDL-R: HDLS carry cholesterol to the liver for elimination. Liver cells respond to estrogen to express a protein receptor for HDLS coded by the HDL-R gene (HDL-R gene contains an estrogen response element.) PFK: codes for an enzyme called phosphofructokinase that is used in the first steps of breaking down glucose for energy in all cells. (Gene has no estrogen response element.) CD3: codes for a cell surface protein produced by immune B cells (Gene has no estrogen response element) MRNA transcripts can be collected from cells, made to glow with a fluorescent dye, and added to a microarray chip containing spots with DNA sequences from each of these genes. (In the depiction of the microarrays below o indicates no binding of the mRNA, and • indicates binding.) HDL-R PFK CD3 A B

Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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HDL-R: HDLS carry cholesterol to the liver for elimination. Liver cells respond to estrogen to express a protein receptor for HDLS coded by the HDL-R gene (HDL-R gene contains an estrogen response element.) PFK: codes for an enzyme called phosphofructokinase that is used in the first steps of breaking down glucose for energy in all cells. (Gene has no estrogen response element.) CD3: codes for a cell surface protein produced by immune B cells (Gene has no estrogen response element) MRNA transcripts can be collected from cells, made to glow with a fluorescent dye, and added to a microarray chip containing spots with DNA sequences from each of these genes. (In the depiction of the microarrays below o indicates no binding of the MRNA, and • indicates binding.) HDL-R PFK CD3 A Which of the gene expression patterns would you expect to see if you used mRNA from immune B cells to add to the microarray? O A O B O C O D
Transcribed Image Text:HDL-R: HDLS carry cholesterol to the liver for elimination. Liver cells respond to estrogen to express a protein receptor for HDLS coded by the HDL-R gene (HDL-R gene contains an estrogen response element.) PFK: codes for an enzyme called phosphofructokinase that is used in the first steps of breaking down glucose for energy in all cells. (Gene has no estrogen response element.) CD3: codes for a cell surface protein produced by immune B cells (Gene has no estrogen response element) MRNA transcripts can be collected from cells, made to glow with a fluorescent dye, and added to a microarray chip containing spots with DNA sequences from each of these genes. (In the depiction of the microarrays below o indicates no binding of the MRNA, and • indicates binding.) HDL-R PFK CD3 A Which of the gene expression patterns would you expect to see if you used mRNA from immune B cells to add to the microarray? O A O B O C O D
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