Arachidonic (AA) acid is an important lipid involved in the production of inflammatory mediators such as prostaglandins. A common treatment of inflammatory conditions is the administration of corticosteroids. These drugs lower the expression of sPLA2. Describe how corticosteroid use leads to the lowering of prostaglandins.
Arachidonic (AA) acid is an important lipid involved in the production of inflammatory mediators such as prostaglandins. A common treatment of inflammatory conditions is the administration of corticosteroids. These drugs lower the expression of sPLA2. Describe how corticosteroid use leads to the lowering of prostaglandins.
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
Related questions
Question
Arachidonic (AA) acid is an important lipid
involved in the production of inflammatory
mediators such as prostaglandins. A common
treatment of inflammatory conditions is the
administration of corticosteroids. These drugs
lower the expression of sPLA2. Describe how
corticosteroid use leads to the lowering of
prostaglandins.
Expert Solution
Introduction
Arachidonic is a polyunsaturated fatty acid that acts as a precursor for the formation of prostaglandins. It is an essential fatty acid obtained from food.
Corticosteroid is a type of steroid medication that is closely related to the natural hormone cortisol. It is used in the treatment of various conditions including inflammation, asthma, rheumatic arthritis, and allergies.
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