Because of prolonged stress created by the COVID 19 pandemic, many people have experienced adrenal fatigue created by the General Adaptation Syndrome. Please explain, using COVID-19 as an example, what this is and how this process develops into adrenal fatigue or organ collapse. Be sure to explain each stage of GAS and which/how hormones are involved in your answer.
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Because of prolonged stress created by the COVID 19 pandemic, many people have experienced adrenal fatigue created by the General Adaptation Syndrome.
Please explain, using COVID-19 as an example, what this is and how this process develops into adrenal fatigue or organ collapse. Be sure to explain each stage of GAS and which/how hormones are involved in your answer.
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- Please answer the Mechanism of action of Sertraline by showing in figures or images or diagrams? Please answer at your own easy words. I will rate you positive if you do so. Please don't use AI for answering this question.Mrs. Anderson, a 45-year-old woman with a history of chronic back pain, has been taking X as prescribed by her rheumatologist for the past eight months. During a routine check-up, her liver function tests revealed significantly elevated liver enzymes. She has not experienced any noticeable symptoms but is now being closely monitored for potential liver-related issues. 2. Propose a pharmacoepidemiological study design to confirm or refute the signal of hepatotoxicity associated with X. Consider factors such as study population, exposure definition, and outcome measures. Discuss the strengths and limitations of your chosen study design? Outline the methods and data sources that could be used to collect information on hepatotoxicity in patients using X.? Discuss how the findings of the study could have regulatory implications. If a significant association is identified, explore how regulatory agencies might implement other measures to ensure patient safety.? Develop communication…Opioids cross the placental barrier, and a newborn of opioid-dependent mother will undergo withdrawal within 6-12 hours of birth. The long-term consequences of prenatal opioid dependence are poorly understood, but it may be best practice to maintain the mother on methadone and treat the infant with opioid rather than withdraw the mother before child delivery. Give some examples of drugs that can be used to reverse withdrawal and which medications can be used for opioid dependence treatment?
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- Answer the following: 1.) an indirect agonist that mimics the action of epinephrine and norepinephrine and either stimulate release or block the reuptake of the naturally occuring sympathomimetics 2.) Toxic concentration of alprazolam 3. The only approved indications for use of this drug is for the treatment of attention-deficit hyperactivity disorder (ADHD) 4. An elevated acetylsalicylic acid serum concentration will decrease serum pH and contributes to 5. the metabolism of acute salicylate poisoning follows what order of metabolism kinetic? 6. In TCA poisoning, why is hemodialysis not recommended as a way of treating patient? 7. after an IV administration of this drug an individual feels a pleasurable experience 8, First generation of the tricyclic antidepressant agents 9. An antidote of choice for iron overdose/poisoning 10. Pediatric toxic dose of salicylates 11. Lethal dose of Amphetamine for children1. https://doi.org/10.1186/s12868-022-00692-1 (link to research) a) In the effect of mitoxantrone on histopathological changes in the brain section of the results section the authors wrote “Post-administration of mitoxantrone to sedentary and exercised groups smaller patches of demyelination with microcyst formation and lymphocytic infiltrates were seen; and bare unmyelinated axons were fewer (Figs. 3D, E, I, J and 4D, E, I, J).” Based on this quote, what is mitoxantrone doing exactly/directly? b) In the histopathological study section of the materials and methods section the authors wrote “Luxol fast blue (LFB) staining was used for assessment of demyelination in the cerebellum and brain stem and scored as described previously by Zhang et al. [21] and illustrated in Table 2.” Why was demyelination assessed in this study?Hydrocortisone is an over-the-counter ointment commonly used to treat eczema. Eczema is a skin condition where a patch of skin becomes irritated and inflamed. It is estimated that approximately 15% of Canadians are affected by eczema at some point in their lives. The active ingredient in hydrocortisone cream is the hormone cortisol. Which of the following statements describes why hydrocortisone is an effective treatment for eczema? Select one: a. Hydrocortisone helps to fight off the skin infection by increasing the immune response. b. Hydrocortisone helps to suppress the skin inflammation by decreasing the immune response. c. Hydrocortisone helps to suppress the skin inflammation by increasing the immune response. d. Hydrocortisone helps to fight off the skin infection by decreasing the immune response.