Which statement correctly identifies how a lipid-soluble hormone that diffuses from the blood and through the interstitial fluid identifies which cells in the tissue to act upon? O The cell closest to the diffusion site. O The presence of a receptor located in the cytoplasm or nucleus specific to the hormone in cells. O The presence of a receptor embedded in the plasma membrane of target cells. O The presence of a channel protein embedded in the plasma membrane for the lipid-soluble hormone to diffuse through.
![Which statement correctly identifies how a lipid-soluble hormone that diffuses from the blood and through the interstitial fluid
identifies which cells in the tissue to act upon?
O The cell closest to the diffusion site.
O The presence of a receptor located in the cytoplasm or nucleus specific to the hormone in cells.
O The presence of a receptor embedded in the plasma membrane of target cells.
O The presence of a channel protein embedded in the plasma membrane for the lipid-soluble hormone to diffuse through.
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Lipid-soluble hormones are a class of hormones that are able to pass through cell membranes due to their hydrophobic (water-repelling) nature. These hormones are also known as nonpolar hormones, as they consist of nonpolar molecules such as steroid hormones, thyroid hormones, and retinoids. Because of their lipid-soluble nature, these hormones can easily cross cell membranes and interact with intracellular receptors located in the cytoplasm or nucleus of target cells. Once they bind to their receptors, lipid-soluble hormones can affect gene expression and other intracellular processes. Examples of lipid-soluble hormones include testosterone, estrogen, progesterone, and cortisol.
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