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Examine the following mRNA transcripts: Wild type: 5' CACUGAUGCACGGAUCAU 3' Mutant: 5' CACUGAUGCACGGAUGAU 3' What kind of mutation is occurring in the mutant sequence compared to the wild type sequence? SECOND BASSE UUU UUC UCU UCc UCA uca Phenylalanine (Phe) UAU UAC UGU Cysteine (Cys) UGC Tyrosine (Tyr) Serine (Ser) UUA UUG UAA -Stop codon UAG -Stop codon UGA -Stop codon uGa -Tryptophan (Trp) Loucine (Leu) CU Ccu CAU CAC Histidine (His) cGu CUc C. CUA Leucine (Leu) Proline (Pro) ainine (Arg) CCA CAA CGA CuG ccG -Glutamine (Gin) CAG AUU ACU ACC ACA ACG AAU AGU AUC -Isoleucine (e) AAC Asparagine (Asn) Serine (Ser) Threonine (Thr) AGC AUA AAA Methionine (Met) Start codon AAG FLysine (Lys) AGA AGG AUG- Arginine (Arg) GcU GUU GUC GUA GUG GAU GGU Aspartic acid (Asp) GAC Valine (Val) Alanine (Ala) Glycine (Gly) GCA GAA GGA GGG Glutamic acid (Glu) GAG O Silent O Missense O Nonsense O Frameshift THIRD BASE PUCODUAO FIRST BASE

Examine the following mRNA transcripts: Wild type: 5' CACUGAUGCACGGAUCAU 3' Mutant: 5' CACUGAUGCACGGAUGAU 3' What kind of mutation is occurring in the mutant sequence compared to the wild type sequence? SECOND BASSE UUU UUC UCU UCc UCA uca Phenylalanine (Phe) UAU UAC UGU Cysteine (Cys) UGC Tyrosine (Tyr) Serine (Ser) UUA UUG UAA -Stop codon UAG -Stop codon UGA -Stop codon uGa -Tryptophan (Trp) Loucine (Leu) CU Ccu CAU CAC Histidine (His) cGu CUc C. CUA Leucine (Leu) Proline (Pro) ainine (Arg) CCA CAA CGA CuG ccG -Glutamine (Gin) CAG AUU ACU ACC ACA ACG AAU AGU AUC -Isoleucine (e) AAC Asparagine (Asn) Serine (Ser) Threonine (Thr) AGC AUA AAA Methionine (Met) Start codon AAG FLysine (Lys) AGA AGG AUG- Arginine (Arg) GcU GUU GUC GUA GUG GAU GGU Aspartic acid (Asp) GAC Valine (Val) Alanine (Ala) Glycine (Gly) GCA GAA GGA GGG Glutamic acid (Glu) GAG O Silent O Missense O Nonsense O Frameshift THIRD BASE PUCODUAO FIRST BASE

Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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**Examine the following mRNA transcripts:** **Wild type:** 5’ CACUGAUGCACGGCAUCAU 3’ **Mutant:** 5’ CACUGAUGCACGGCAUGAU 3’ **What kind of mutation is occurring in the mutant sequence compared to the wild type sequence?** **Genetic Code Chart:** The chart is a codon table used to identify which amino acid corresponds to each mRNA codon. It is organized by the first, second, and third bases of the codon: - **First Base (Y-Axis):** U, C, A, G - **Second Base (X-Axis):** U, C, A, G - **Third Base (Z-Axis on the right side):** U, C, A, G For example, the codon AUG corresponds to Methionine (Met) and also acts as the start codon. **Options for Type of Mutation:** - Silent - Missense - Nonsense - Frameshift Use the chart to determine the amino acid sequence for both the wild type and mutant mRNA transcripts and identify the type of mutation that has occurred.
Transcribed Image Text:**Examine the following mRNA transcripts:** **Wild type:** 5’ CACUGAUGCACGGCAUCAU 3’ **Mutant:** 5’ CACUGAUGCACGGCAUGAU 3’ **What kind of mutation is occurring in the mutant sequence compared to the wild type sequence?** **Genetic Code Chart:** The chart is a codon table used to identify which amino acid corresponds to each mRNA codon. It is organized by the first, second, and third bases of the codon: - **First Base (Y-Axis):** U, C, A, G - **Second Base (X-Axis):** U, C, A, G - **Third Base (Z-Axis on the right side):** U, C, A, G For example, the codon AUG corresponds to Methionine (Met) and also acts as the start codon. **Options for Type of Mutation:** - Silent - Missense - Nonsense - Frameshift Use the chart to determine the amino acid sequence for both the wild type and mutant mRNA transcripts and identify the type of mutation that has occurred.
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