Consider the hypothetical serine protease, which shows the specificity pockets. The S, pocket has a glutamic acid in the bottom, the Sz pocket is small and hydrophobic, and the S,' pocket is deep and hydrophobic. Suggest an amino acid sequence that this protease would cleave. H. R2 HR Which of the sequences would this protease cleave? O Lys-Ala-Leu Ala-Lys-Leu Leu-Ala-Lys Ala-Leu-Lys Leu-Lys-Ala C=O

Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
icon
Related questions
Question
Consider the hypothetical serine protease, which shows the
specificity pockets. The S, pocket has a glutamic acid in
the bottom, the S, pocket is small and hydrophobic, and the
S,' pocket is deep and hydrophobic. Suggest an amino acid
sequence that this protease would cleave.
HRY
S2
Si
Which of the sequences would this protease cleave?
O Lys-Ala-Leu
O Ala-Lys-Leu
Leu-Ala-Lys
Ala-Leu-Lys
O Leu-Lys-Ala
O Lys-Leu-Ala
C=O
Transcribed Image Text:Consider the hypothetical serine protease, which shows the specificity pockets. The S, pocket has a glutamic acid in the bottom, the S, pocket is small and hydrophobic, and the S,' pocket is deep and hydrophobic. Suggest an amino acid sequence that this protease would cleave. HRY S2 Si Which of the sequences would this protease cleave? O Lys-Ala-Leu O Ala-Lys-Leu Leu-Ala-Lys Ala-Leu-Lys O Leu-Lys-Ala O Lys-Leu-Ala C=O
Expert Solution
trending now

Trending now

This is a popular solution!

steps

Step by step

Solved in 2 steps

Blurred answer
Knowledge Booster
Membrane chemistry
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biochemistry and related others by exploring similar questions and additional content below.
Similar questions
Recommended textbooks for you
Biochemistry
Biochemistry
Biochemistry
ISBN:
9781319114671
Author:
Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:
W. H. Freeman
Lehninger Principles of Biochemistry
Lehninger Principles of Biochemistry
Biochemistry
ISBN:
9781464126116
Author:
David L. Nelson, Michael M. Cox
Publisher:
W. H. Freeman
Fundamentals of Biochemistry: Life at the Molecul…
Fundamentals of Biochemistry: Life at the Molecul…
Biochemistry
ISBN:
9781118918401
Author:
Donald Voet, Judith G. Voet, Charlotte W. Pratt
Publisher:
WILEY
Biochemistry
Biochemistry
Biochemistry
ISBN:
9781305961135
Author:
Mary K. Campbell, Shawn O. Farrell, Owen M. McDougal
Publisher:
Cengage Learning
Biochemistry
Biochemistry
Biochemistry
ISBN:
9781305577206
Author:
Reginald H. Garrett, Charles M. Grisham
Publisher:
Cengage Learning
Fundamentals of General, Organic, and Biological …
Fundamentals of General, Organic, and Biological …
Biochemistry
ISBN:
9780134015187
Author:
John E. McMurry, David S. Ballantine, Carl A. Hoeger, Virginia E. Peterson
Publisher:
PEARSON