al mRNA: 5’- AUG GGC UCG ACC UUG -3’ Mutant mRNA 1: 5’- AUG GGC UAG ACC UUG -3’ Mutant mRNA 2: 5’- AUG GGC UCG ACU UUG -3’ Mutant mRNA 3: 5’- AUG GGC UCG AGC UUG -3’ Mutant mRNA 4: 5’- AUG GGC UCG AUC UUG -3’ A. Write out the protein sequence for the original protein. 1. Three letter sequence (write with one space in between, i.e. Val Leu Gly) 2. One letter sequence (write out with one space between, i.e. V L G) B. Characterize the mutants (#1-4) as silent, nonsense, or missense mutations.
al mRNA: 5’- AUG GGC UCG ACC UUG -3’ Mutant mRNA 1: 5’- AUG GGC UAG ACC UUG -3’ Mutant mRNA 2: 5’- AUG GGC UCG ACU UUG -3’ Mutant mRNA 3: 5’- AUG GGC UCG AGC UUG -3’ Mutant mRNA 4: 5’- AUG GGC UCG AUC UUG -3’ A. Write out the protein sequence for the original protein. 1. Three letter sequence (write with one space in between, i.e. Val Leu Gly) 2. One letter sequence (write out with one space between, i.e. V L G) B. Characterize the mutants (#1-4) as silent, nonsense, or missense mutations.
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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The following mutants are observed in a gene coded for a ribosomal protein. The mutations are highlighted:
Original mRNA: 5’- AUG GGC UCG ACC UUG -3’
Mutant mRNA 1: 5’- AUG GGC UAG ACC UUG -3’
Mutant mRNA 2: 5’- AUG GGC UCG ACU UUG -3’
Mutant mRNA 3: 5’- AUG GGC UCG AGC UUG -3’
Mutant mRNA 4: 5’- AUG GGC UCG AUC UUG -3’
A. Write out the protein sequence for the original protein.
1. Three letter sequence (write with one space in between, i.e. Val Leu Gly)
2. One letter sequence (write out with one space between, i.e. V L G)
B. Characterize the mutants (#1-4) as silent, nonsense, or missense mutations.
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