Homework Help is Here – Start Your Trial Now!
Science
Biology
Which of the following characterize RNA polymerase Il transcriptional termination in eukaryotes? Endonuclease cleavage of the RNA transcript and 5' to 3' exonuclease activity a protein known as Ratl None of the provided answers, transcriptional termination occurs in prokaryotes. Recognition of the transcriptional stop codon by a release factor. Hairpin structure formation on the newly synthesized RNA molecule which disrupts the DNA-RNA hybrid at a poly-U RNA sequence Binding of the Rho protein.

Which of the following characterize RNA polymerase Il transcriptional termination in eukaryotes? Endonuclease cleavage of the RNA transcript and 5' to 3' exonuclease activity a protein known as Ratl None of the provided answers, transcriptional termination occurs in prokaryotes. Recognition of the transcriptional stop codon by a release factor. Hairpin structure formation on the newly synthesized RNA molecule which disrupts the DNA-RNA hybrid at a poly-U RNA sequence Binding of the Rho protein.

Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
See similar textbooks
icon
Related questions
icon
Concept explainers
Question
### Transcriptional Termination in Eukaryotes **Question:** Which of the following characterize RNA polymerase II transcriptional termination in eukaryotes? **Options:** 1. Endonuclease cleavage of the RNA transcript and 5’ to 3’ exonuclease activity a protein known as Rat1. 2. None of the provided answers, transcriptional termination occurs in prokaryotes. 3. Recognition of the transcriptional stop codon by a release factor. 4. Hairpin structure formation on the newly synthesized RNA molecule which disrupts the DNA-RNA hybrid at a poly-U RNA sequence. 5. Binding of the Rho protein. ### Explanation of Options: 1. **Endonuclease Cleavage and Rat1 Activity:** - This option suggests that termination involves the cleavage of the RNA transcript by an endonuclease enzyme. Following this, a 5' to 3' exonuclease activity by a protein known as Rat1 further degrades the RNA, leading to termination. 2. **Prokaryotic Transcription:** - This option indicates that the provided answers are not applicable to prokaryotic transcription, implying that the correct mechanism is unique to eukaryotes. 3. **Stop Codon and Release Factor:** - This option implies recognition of a stop codon on the RNA by a release factor, which is more commonly associated with translation (protein synthesis) rather than transcription. 4. **Hairpin Structure Formation:** - This option suggests that the formation of a hairpin structure on the RNA disrupts the DNA-RNA hybrid, typically seen in prokaryotic Rho-independent termination but not in eukaryotic systems. 5. **Rho Protein Binding:** - This option involves the binding of the Rho protein to terminate transcription, a mechanism exclusive to prokaryotes and not relevant to eukaryotic RNA polymerase II. **Explanation of Correct Answer:** - The mechanism of transcriptional termination in eukaryotes commonly involves the cleavage of the RNA transcript followed by degradation through exonuclease activity. Rat1 plays a significant role in this process. Hence, the most accurate characterization would involve endonuclease cleavage followed by 5' to 3' exonuclease activity of Rat1 (Option 1). For a more detailed understanding, students are encouraged to review the molecular mechanisms of transcription and termination, focusing on the
Transcribed Image Text:### Transcriptional Termination in Eukaryotes **Question:** Which of the following characterize RNA polymerase II transcriptional termination in eukaryotes? **Options:** 1. Endonuclease cleavage of the RNA transcript and 5’ to 3’ exonuclease activity a protein known as Rat1. 2. None of the provided answers, transcriptional termination occurs in prokaryotes. 3. Recognition of the transcriptional stop codon by a release factor. 4. Hairpin structure formation on the newly synthesized RNA molecule which disrupts the DNA-RNA hybrid at a poly-U RNA sequence. 5. Binding of the Rho protein. ### Explanation of Options: 1. **Endonuclease Cleavage and Rat1 Activity:** - This option suggests that termination involves the cleavage of the RNA transcript by an endonuclease enzyme. Following this, a 5' to 3' exonuclease activity by a protein known as Rat1 further degrades the RNA, leading to termination. 2. **Prokaryotic Transcription:** - This option indicates that the provided answers are not applicable to prokaryotic transcription, implying that the correct mechanism is unique to eukaryotes. 3. **Stop Codon and Release Factor:** - This option implies recognition of a stop codon on the RNA by a release factor, which is more commonly associated with translation (protein synthesis) rather than transcription. 4. **Hairpin Structure Formation:** - This option suggests that the formation of a hairpin structure on the RNA disrupts the DNA-RNA hybrid, typically seen in prokaryotic Rho-independent termination but not in eukaryotic systems. 5. **Rho Protein Binding:** - This option involves the binding of the Rho protein to terminate transcription, a mechanism exclusive to prokaryotes and not relevant to eukaryotic RNA polymerase II. **Explanation of Correct Answer:** - The mechanism of transcriptional termination in eukaryotes commonly involves the cleavage of the RNA transcript followed by degradation through exonuclease activity. Rat1 plays a significant role in this process. Hence, the most accurate characterization would involve endonuclease cleavage followed by 5' to 3' exonuclease activity of Rat1 (Option 1). For a more detailed understanding, students are encouraged to review the molecular mechanisms of transcription and termination, focusing on the
Expert Solution
trending now

Trending now

This is a popular solution!

steps

Step by step

Solved in 2 steps

SEE SOLUTIONCheck out a sample Q&A here
Blurred answer
Knowledge Booster
Bacterial genomics
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.
Similar questions
  • SEE MORE QUESTIONS
Recommended textbooks for you
Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
Biology
ISBN:
9780134580999
Author:
Elaine N. Marieb, Katja N. Hoehn
Publisher:
PEARSON
Biology 2e
Biology 2e
Biology
ISBN:
9781947172517
Author:
Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:
OpenStax
Anatomy & Physiology
Anatomy & Physiology
Biology
ISBN:
9781259398629
Author:
McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa Stouter
Publisher:
Mcgraw Hill Education,
Molecular Biology of the Cell (Sixth Edition)
Molecular Biology of the Cell (Sixth Edition)
Biology
ISBN:
9780815344322
Author:
Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter
Publisher:
W. W. Norton & Company
Laboratory Manual For Human Anatomy & Physiology
Laboratory Manual For Human Anatomy & Physiology
Biology
ISBN:
9781260159363
Author:
Martin, Terry R., Prentice-craver, Cynthia
Publisher:
McGraw-Hill Publishing Co.
Inquiry Into Life (16th Edition)
Inquiry Into Life (16th Edition)
Biology
ISBN:
9781260231700
Author:
Sylvia S. Mader, Michael Windelspecht
Publisher:
McGraw Hill Education
SEE MORE TEXTBOOKS