1. If there were only two alleles of TAS2R38 (AVI and PAV) in the human population, what are the possible allelic combinations in diploid cells? 2. For the sake of simplicity, assume that only the amino acids Pro, Ala and Val make up the functioning active site pocket within the taste receptor TAS2R38. Using your knowledge of amino acid properties, describe the environment of the active site. Is it surprising that changing these amino acids to Ala, Val and Iso, respectively, inhibits the receptor from binding PTC?

1. If there were only two alleles of TAS2R38 (AVI and PAV) in the human population, what are the possible allelic combinations in diploid cells? 2. For the sake of simplicity, assume that only the amino acids Pro, Ala and Val make up the functioning active site pocket within the taste receptor TAS2R38. Using your knowledge of amino acid properties, describe the environment of the active site. Is it surprising that changing these amino acids to Ala, Val and Iso, respectively, inhibits the receptor from binding PTC?

Human Anatomy & Physiology (11th Edition)

11th Edition

ISBN:9780134580999

Author:Elaine N. Marieb, Katja N. Hoehn

Publisher:Elaine N. Marieb, Katja N. Hoehn

Chapter1: The Human Body: An Orientation

Section: Chapter Questions

Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...

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