LH-P-27-0328-WhEEL

pdf

School

Johns Hopkins University *

*We aren’t endorsed by this school

Course

410.302.81

Subject

Chemistry

Date

Oct 30, 2023

Type

pdf

Pages

1

Uploaded by DeanNeutronHedgehog15

Report
CHEM 240 • Pelkey Hobart and William Smith Colleges Fall 2016 L ECTURE H ANDOUT #26 • Page 1 of 1 L ECTURE H ANDOUT #26: R EACTION R OADMAP D ATE : W EDNESDAY , N OVEMBER 2 Me Me OH (OR) Br Me Br Me H OH O O H H Me H Me Br Br Me OH OH 1. O 3 2. Me 2 S (or Zn) 1. BH 3 , THF 2. H 2 O 2 , NaOH CHBr 3 , KO t Bu Br 2 , CH 2 Cl 2 O O OH 1. O 3 2. H 2 O 2 Me H Br Me H Cl Me H OTs PBr 3 Me H CN 1. LiAlH 4 2. H 3 O + (work-up) Me OH R Me H OMe racemic racemic Color-coded Reactions Key addition reactions (in blue) substitution reactions (in green) elimination reactions (in red) other reactions (in purple) 1. OsO 4 2. aq. NaOH (or KMnO 4 , aq. NaOH) Br 2 , H 2 O (or ROH) Me Br Br racemic racemic racemic Me OH (OR) Me OH (OR) H 2 SO 4 (cat.), H 2 O (or ROH) 1. Hg(OAc) 2 , H 2 O (or ROH) 2. NaBH 4 HBr H 2 , Pd/C Br 2 , h ν CH 2 N 2 , h ν (or Δ ) racemic m -CPBA (or CF 3 CO 3 H) Me O Me H H Me OH H Me OH OH (OR) Me OH (OR) OH 1. RMgBr (or RLi) 2. H 3 O + work-up racemic NaOH, H 2 O (or NaOR, ROH) H 2 SO 4 (cat.), H 2 O (ROH) HBr radical S N 1 t-BuOK Me NaOH H 2 SO 4 , benzene, Δ (Dean-Stark) 1. NaH 2. MeI (or R–X) PPh 3 , CBr 4 TsCl, Et 3 N NaCN, DMF E2 E2 E1 epoxide ring opening reactions S N 2 S N 1/S N 2 S N 2 S N 2 reactions with bromonium intermediates Me t-BuOK E2 (OR) NaN 3 , DMSO Me H N 3 S N 2 Me H Br S N 1/S N 2 SOCl 2 NaN 3 , DMF S N 2 Me H N 3
Discover more documents: Sign up today!
Unlock a world of knowledge! Explore tailored content for a richer learning experience. Here's what you'll get:
  • Access to all documents
  • Unlimited textbook solutions
  • 24/7 expert homework help

Browse Popular Homework Q&A

Q: 103.3 5 [ ₁ (+² -5 (x² + 2) dx X
Q: Consider the transformer with the secondary terminated in a load resistance R, as shown. This as a…
Q: Vector A has x and y components of -9.00 cm and 13.0 cm, respectively; vector B has x and y…
Q: 3-14 - Values of Trigonometric Functions Use an Addition or Subtraction Formula to find the exact…
Q: Evaluate S(4sinx + 3cosx - (5csc^2 x)dx
Q: Coenzyme A (abbreviated CoA, HS-CoA, or CoA-SH) is one of the major coenzymes that play a central…
Q: The structure of a sphingomyelin that contains sphingosine, stearic acid, phosphate, and…
Q: Consider the following functions. 3 f(x) g(x) X + 5 Find (f + g)(x). 8x + 15 (No Response) Find the…
Q: FUSA-express is a small express delivery company with hubs in Los Angeles, CA, Denver, CO; Dallas,…
Q: 9 Calculate the flux of the vector field (x³, y³), out of the annular region between the x² + y² =…
Q: A displacement vector has components Ax = –6 m and Ay = –10 m.  What angle does this vector make…
Q: If $4,000 invested in a bank account for 5 years, compounded quarterly, amounts to $4,871.10, what…
Q: What is the product of the oxidation of 2-methyl- 1-octanol? If no reaction, select "None". O…
Q: Find the indicated IQ score. The graph to the right depicts IQ scores of​ adults, and those scores…
Q: Suppose that Y is an exponential random variable with λ = 4. Find. P[Y > (E(Y) + 2√√Var(Y))].
Q: Using the Kf and Kb équati -7.03 °C-kg-mol. Calculate хтно A certain liquid X has a normal freezing…
Q: fa rock is dropped from a height of 217 ft, its poistion t seconds after it is dropped until it hits…
Q: A galvanic cell at a temperature of 25.0 °C is powered by the following redox reaction: 3+ 2+ 2 Cr³+…
Q: 30 - With reference to the Security Market Line, assume for the current time period the Risk-Free…
Q: Sales Forecast and Flexible Budget Olympus, Inc., manufactures three models of mattresses: the…
Q: Give the IUPAC name of the ester depicted below. O butyl ethanoate O butyl ethanoic acid O ethyl…
Q: Compute equivalent units using the weighted average method. Attached is 2 screenshots of the entire…