Coenzyme A (abbreviated CoA, HS-CoA, or CoA-SH) is one of the major coenzymes that play a central role in metabolic pathways. An important role of coenzyme A is to prepare molecules containing acyl group (R-CO-) for reactions with enzymes by forming a thioester bond with them as shown in the following box: Alkyl group O Thiol group R-C-OH+ HS-CoA Acyl group Coenzyme A Acyl CoA synthetase +ATP-R-C-S-CoA+AMP+PP Acyl CoA Thioester bond Deduce the missing product for the following reaction involving coenzyme A. CH₂-CH₂-CH₂-C-OH + HS-CoA + ATP Acyl COA synthetase ? +AMP+ PP₁

Chemistry
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ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
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Chapter1: Chemical Foundations
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DF
trasc
Coenzyme A (abbreviated CoA, HS-CoA, or CoA-SH) is one of the
major coenzymes that play a central role in metabolic pathways. An
important role of coenzyme A is to prepare molecules containing
acyl group (R-CO-) for reactions with enzymes by forming a
thioester bond with them as shown in the following box:
PDF
Tebb til
PDF
Alkyl group
O
R-C-
Acyl group
Thiol group
O
OH+ HS-CoA +ATP
Coenzyme A
Acyl COA
synthetase
O
||
CH₂-CH₂-CH₂-C-OH + HS-CoA + ATP
O
Deduce the missing product for the following reaction involving
coenzyme A.
→R-C-S-CoA+AMP+PP
CH₂-CH₂-CH₂-C-S-CH₂
8
O Thioester bond
S
CH₂-CH₂-CH₂-C-0-CoA
Acyl CoA
Acyl CoA
synthetase
? + AMP + PP₁
O Search
PD
PDR
uniz
recor
p
PC
lab
PDF
accin
per w
A
Gle
Transcribed Image Text:P DF trasc Coenzyme A (abbreviated CoA, HS-CoA, or CoA-SH) is one of the major coenzymes that play a central role in metabolic pathways. An important role of coenzyme A is to prepare molecules containing acyl group (R-CO-) for reactions with enzymes by forming a thioester bond with them as shown in the following box: PDF Tebb til PDF Alkyl group O R-C- Acyl group Thiol group O OH+ HS-CoA +ATP Coenzyme A Acyl COA synthetase O || CH₂-CH₂-CH₂-C-OH + HS-CoA + ATP O Deduce the missing product for the following reaction involving coenzyme A. →R-C-S-CoA+AMP+PP CH₂-CH₂-CH₂-C-S-CH₂ 8 O Thioester bond S CH₂-CH₂-CH₂-C-0-CoA Acyl CoA Acyl CoA synthetase ? + AMP + PP₁ O Search PD PDR uniz recor p PC lab PDF accin per w A Gle
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