Biochemistry, The Molecular Basis of Life, 6th Edition
Biochemistry, The Molecular Basis of Life, 6th Edition
6th Edition
ISBN: 9780190259204
Author: Trudy McKee, James R. McKee
Publisher: Oxford University Press
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Chapter 6, Problem 80TQ
Summary Introduction

To review:

The following Km values for the enzyme ADH1 in Saccharomyces cerevisiae for ethanol and acetaldehyde are given. The possible reaso, nased on Km values, that explains the role of ADH1 enzyme in the ethanol metabolism of the organism is to be listed.

Km (ethanol) Km (acetaldehyde)
ADH1 20,000 µM 1500 µM

Introduction:

The organism Saccharomyces cerevisiae produces ethanol by utilizing glucose moleculesirrespective of the presence or absence of oxygen. The enzyme, alcohol dehydrogenase (ADH) catalyzes this reaction. Km is the equilibrium constant, which signifies the affinity of an enzyme for its substrate. The value of Km of a particular enzyme may change according to the substrate.

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Biochemistry, The Molecular Basis of Life, 6th Edition

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