Biochemistry, The Molecular Basis of Life, 6th Edition
Biochemistry, The Molecular Basis of Life, 6th Edition
6th Edition
ISBN: 9780190259204
Author: Trudy McKee, James R. McKee
Publisher: Oxford University Press
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Chapter 6, Problem 4Q
Summary Introduction

To review:

The products formed when iodoacetamide reacts with an enzyme containing cysteine residue.

Introduction:

Irreversible inhibitors are typical enzyme inhibitors, which have a tendency to form covalent associations with enzymes. This covalent association results in the inactivation of the enzyme, because one of the key catalytic residues of the enzyme becomes modified. A characteristic inhibitor of most of the cysteine-containing amino acids is iodoacetate.

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Chapter 6 Solutions

Biochemistry, The Molecular Basis of Life, 6th Edition

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