Chapter 6, Problem 62TQ

Summary Introduction

To review:

The transition state for each step involved in the exothermic hydrolysis of tertiary-butyl chloride, resulting in t (tertiary)-butyl alcohol and chloride ions. The reactions are given as follows:

Introduction:

A biochemical reaction follows the same rules as followed by a chemical reaction occurring in a laboratory. There is a formation of electron deficient species (electrophiles), electron rich species (nucleophiles), as well as least stable transition states. The transition state is the structural form of reactant moleculesand possesses the highest energy, compared toproducts and reactants of the reaction.