Biology: The Dynamic Science (MindTap Course List)
Biology: The Dynamic Science (MindTap Course List)
4th Edition
ISBN: 9781305389892
Author: Peter J. Russell, Paul E. Hertz, Beverly McMillan
Publisher: Cengage Learning
bartleby

Concept explainers

bartleby

Videos

Textbook Question
Book Icon
Chapter 47, Problem 1ITD

The human AMY-1 gene encodes salivary amylase, an enzyme that breaks down starch. The number of copies of this gene varies, and people who have more copies generally make more of the enzyme. In addition, the average number of AMY-1 copies differs among cultural groups.

George Perry and his colleagues hypothesized that duplications of the AMY-1 gene would confer a selective advantage in cultures in which starch is a large part of the diet. To test this hypothesis, the scientists compared the number of copies of the AMY-1 gene among members of seven cultural groups that differed in their traditional diets. The Figure shows their results.

Starchy tubers are a mainstay of Hadza hunter-gatherers in Africa, whereas fishing sustains Siberia’s Yakut. Almost 60% of Yakut had fewer than 5 copies of the AMY-1 gene. What percentage of the Hadza had fewer than 5 copies?

Chapter 47, Problem 1ITD, The human AMY-1 gene encodes salivary amylase, an enzyme that breaks down starch. The number of

FIGURENumber of copies of the AMY-1 gene among members of cultures with traditional high-starch or low-starch diets.

Source: G. Perry et al. 2007. Diet and the evolution of human amylase gene copy number variation. Nature Genetics 39:1256–1260.

Blurred answer
Students have asked these similar questions
When the O2 supply from blood fails to meet the demand of O2-consuming cells, oxygen deprivation (hypoxia) occurs. This is common, for example, in exercising muscle. It has been recognized for over 100 years that O2- deprived cells show increased conversion of glucose to lactate, known as the Pasteur effect. Activation of the Pasteur effect during hypoxia is mediated by hypoxia-inducible factor-1 (HIF-1). HIF-1 is a transcription factor that upregulates the expression of several glycolytic enzymes that support the increased glycolytic ATP production as mitochondria become starved for O2. At the same time glycolysis is increasing, the rate of mitochondrial respiration decreases. New research reveals that in addition to upregulating enzymes in the glycolytic pathway, HIF-1 also induces the expression of cytoplasmic lactate dehydrogenase (LDH) and mitochondrial pyruvate dehydrogenase kinase (PDK).(a) Explain why glucose consumption must increase in hypoxic tissues toprovide the same…
When the O2 supply from blood fails to meet the demand of O2-consuming cells, oxygen deprivation (hypoxia) occurs. This is common, for example,in exercising muscle. It has been recognized for over 100 years that O2-deprived cells show increased conversion of glucose to lactate, known as the Pasteur effect. Activation of the Pasteur effect during hypoxia is mediated by hypoxia-inducible factor-1 (HIF-1). HIF-1 is a transcription factor that upregulates the expression of several glycolytic enzymes that support the increased glycolytic ATP production as mitochondria become starved for O2. At the same time glycolysis is increasing, the rate of mitochondrial respiration decreases. New research reveals that in addition to upregulating enzymes in the glycolytic pathway, HIF-1 also induces the expression of cytoplasmic lactate dehydrogenase (LDH) and mitochondrial pyruvate dehydrogenase kinase (PDK).(a) Explain why glucose consumption must increase in hypoxic tissues toprovide the same amount…
The cytochrome P450 system metabolizes many medicinally useful drugs. Although all human beings have the same number of P450 genes, individual polymorphisms exist that alter the specificity and efficiency of the proteins encoded by the genes. How could knowledge of individual polymorphisms be useful clinically?
Knowledge Booster
Background pattern image
Biology
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.
Similar questions
SEE MORE QUESTIONS
Recommended textbooks for you
Text book image
Biology: The Dynamic Science (MindTap Course List)
Biology
ISBN:9781305389892
Author:Peter J. Russell, Paul E. Hertz, Beverly McMillan
Publisher:Cengage Learning
Text book image
Ebk:Nutrition & Diet Therapy
Health & Nutrition
ISBN:9780357391747
Author:DEBRUYNE
Publisher:Cengage
Text book image
Human Biology (MindTap Course List)
Biology
ISBN:9781305112100
Author:Cecie Starr, Beverly McMillan
Publisher:Cengage Learning
Text book image
Human Heredity: Principles and Issues (MindTap Co...
Biology
ISBN:9781305251052
Author:Michael Cummings
Publisher:Cengage Learning
Nutrition and Diet - GCSE Biology (9-1); Author: Mr Exham Biology;https://www.youtube.com/watch?v=SFE1DfAlipo;License: Standard Youtube License