EBK FUNDAMENTALS OF BIOSTATISTICS
8th Edition
ISBN: 9781305465510
Author: Rosner
Publisher: YUZU
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Textbook Question
Chapter 3, Problem 38P
Suppose that a disease is inherited via an autosomal recessive
What is the probability that exactly one sibling is affected?
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Question 4
An article in Quality Progress (May 2011, pp. 42-48) describes the use of factorial experiments to improve a
silver powder production process. This product is used in conductive pastes to manufacture a wide variety of
products ranging from silicon wafers to elastic membrane switches. Powder density (g/cm²) and surface area
(cm/g) are the two critical characteristics of this product. The experiments involved three factors: reaction
temperature, ammonium percentage, stirring rate. Each of these factors had two levels, and the design was
replicated twice. The design is shown in Table 3.
A222222222222233
Stir Rate
(RPM)
Ammonium
(%)
Table 3: Silver Powder Experiment from Exercise 13.23
Temperature
(°C)
Density
Surface Area
100
8
14.68
0.40
100
8
15.18
0.43
30
100
8
15.12
0.42
30
100
17.48
0.41
150
7.54
0.69
150
8
6.66
0.67
30
150
8
12.46
0.52
30
150
8
12.62
0.36
100
40
10.95
0.58
100
40
17.68
0.43
30
100
40
12.65
0.57
30
100
40
15.96
0.54
150
40
8.03
0.68
150
40
8.84
0.75
30
150…
-
+
++
Table 2: Crack Experiment for Exercise 2
A B C D Treatment Combination
(1)
Replicate
I II
7.037
6.376
14.707 15.219
|++++ 1
བྱ॰༤༠སྦྱོ སྦྱོཋཏྟཱུ
a
b
ab
11.635 12.089
17.273 17.815
с
ас
10.403 10.151
4.368 4.098
bc
abc
9.360 9.253
13.440 12.923
d
8.561 8.951
ad
16.867 17.052
bd
13.876 13.658
abd
19.824 19.639
cd
11.846 12.337
acd
6.125
5.904
bcd
11.190 10.935
abcd
15.653 15.053
Question 3
Continuation of Exercise 2. One of the variables in the experiment described in Exercise 2, heat treatment
method (C), is a categorical variable. Assume that the remaining factors are continuous.
(a) Write two regression models for predicting crack length, one for each level of the heat treatment method
variable. What differences, if any, do you notice in these two equations?
(b) Generate appropriate response surface contour plots for the two regression models in part (a).
(c) What set of conditions would you recommend for the factors A, B, and D if you use heat treatment method
C = +?
(d) Repeat…
Question 2
A nickel-titanium alloy is used to make components for jet turbine aircraft engines. Cracking is a potentially
serious problem in the final part because it can lead to nonrecoverable failure. A test is run at the parts producer
to determine the effect of four factors on cracks. The four factors are: pouring temperature (A), titanium content
(B), heat treatment method (C), amount of grain refiner used (D). Two replicates of a 24 design are run, and
the length of crack (in mm x10-2) induced in a sample coupon subjected to a standard test is measured. The
data are shown in Table 2.
1
(a) Estimate the factor effects. Which factor effects appear to be large?
(b) Conduct an analysis of variance. Do any of the factors affect cracking? Use a = 0.05.
(c) Write down a regression model that can be used to predict crack length as a function of the significant
main effects and interactions you have identified in part (b).
(d) Analyze the residuals from this experiment.
(e) Is there an…
Chapter 3 Solutions
EBK FUNDAMENTALS OF BIOSTATISTICS
Ch. 3.6 - What is the frequency definition of probability?Ch. 3.6 - What is the difference between independent and...Ch. 3.6 - What are mutually exclusive events?Ch. 3.6 - What is the addition law of probability?Ch. 3.6 - What is conditional probability? How does it...Ch. 3.6 - What is relative risk? How do you interpret it?Ch. 3.6 - Prob. B.1RECh. 3.6 - Suppose the rate of type II diabetes mellitus (DM)...Ch. 3.7 - What is the sensitivity and specificity of a...Ch. 3.7 - What are the PV+ and PV of a screening test? How...
Ch. 3.7 - Prob. C.3RECh. 3.7 - What is Bayes rule? How is it used?Ch. 3.7 - Prob. D.2RECh. 3.7 - Prob. D.3RECh. 3.7 - Prob. D.4RECh. 3.10 - Suppose that of 25 students in a class, 5 are...Ch. 3.10 - Suppose 50 HIV-positive men are identified, 5 of...Ch. 3 - Consider a family with a mother, father, and two...Ch. 3 - Consider a family with a mother, father, and two...Ch. 3 - Consider a family with a mother, father, and two...Ch. 3 - Consider a family with a mother, father, and two...Ch. 3 - Consider a family with a mother, father, and two...Ch. 3 - Consider a family with a mother, father, and two...Ch. 3 - Consider a family with a mother, father, and two...Ch. 3 - Consider a family with a mother, father, and two...Ch. 3 - Consider a family with a mother, father, and two...Ch. 3 - Consider a family with a mother, father, and two...Ch. 3 - Prob. 11PCh. 3 - Suppose an influenza epidemic strikes a city. In...Ch. 3 - Suppose there is a 20% chance each child will get...Ch. 3 - Suppose there is a 20% chance each child will get...Ch. 3 - Suppose there is a 20% chance each child will get...Ch. 3 - Mental Health Estimates of the prevalence of...Ch. 3 - Mental Health Estimates of the prevalence of...Ch. 3 - Mental Health Estimates of the prevalence of...Ch. 3 - Mental Health Estimates of the prevalence of...Ch. 3 - Estimates of the prevalence of Alzheimers disease...Ch. 3 - Estimates of the prevalence of Alzheimers disease...Ch. 3 - Estimates of the prevalence of Alzheimers disease...Ch. 3 - Estimates of the prevalence of Alzheimers disease...Ch. 3 - Estimates of the prevalence of Alzheimers disease...Ch. 3 - Estimates of the prevalence of Alzheimers disease...Ch. 3 - Suppose a study of Alzheimers disease is proposed...Ch. 3 - Suppose a study of Alzheimers disease is proposed...Ch. 3 - Commonly used vaccines for influenza are trivalent...Ch. 3 - Prob. 29PCh. 3 - Prob. 30PCh. 3 - Prob. 31PCh. 3 - Genetics Suppose that a disease is inherited via a...Ch. 3 - Genetics Suppose that a disease is inherited via a...Ch. 3 - Genetics Suppose that a disease is inherited via a...Ch. 3 - Prob. 35PCh. 3 - Prob. 36PCh. 3 - Suppose that a disease is inherited via an...Ch. 3 - Suppose that a disease is inherited via an...Ch. 3 - Prob. 39PCh. 3 - Suppose that a disease is inherited via a...Ch. 3 - Suppose that a disease is inherited via a...Ch. 3 - Suppose that a disease is inherited via a...Ch. 3 - Suppose that a disease is inherited via a...Ch. 3 - Prob. 44PCh. 3 - Prob. 45PCh. 3 - Prob. 46PCh. 3 - Prob. 47PCh. 3 - Prob. 48PCh. 3 - Prob. 49PCh. 3 - Obstetrics The following data are derived from the...Ch. 3 - Obstetrics The following data are derived from the...Ch. 3 - Obstetrics The following data are derived from the...Ch. 3 - Pulmonary Disease The familial aggregation of...Ch. 3 - Pulmonary Disease The familial aggregation of...Ch. 3 - Suppose, alternatively, that if the father is a...Ch. 3 - Suppose, alternatively, that if the father is a...Ch. 3 - Prob. 57PCh. 3 - The familial aggregation of respiratory disease is...Ch. 3 - The familial aggregation of respiratory disease is...Ch. 3 - The familial aggregation of respiratory disease is...Ch. 3 - The familial aggregation of respiratory disease is...Ch. 3 - Pulmonary Disease The familial aggregation of...Ch. 3 - Pulmonary Disease The familial aggregation of...Ch. 3 - Genetics, Obstetrics Precise quantification of...Ch. 3 - Precise quantification of smoking during pregnancy...Ch. 3 - Precise quantification of smoking during pregnancy...Ch. 3 - What is another name for this quantity? Suppose it...Ch. 3 - Research into cigarette-smoking habits, smoking...Ch. 3 - Research into cigarette-smoking habits, smoking...Ch. 3 - Research into cigarette-smoking habits, smoking...Ch. 3 - Research into cigarette-smoking habits, smoking...Ch. 3 - Research into cigarette-smoking habits, smoking...Ch. 3 - Research into cigarette-smoking habits, smoking...Ch. 3 - Pulmonary Disease Research into cigarette-smoking...Ch. 3 - Pulmonary Disease Research into cigarette-smoking...Ch. 3 - Laboratory measures of cardiovascular reactivity...Ch. 3 - Laboratory measures of cardiovascular reactivity...Ch. 3 - Laboratory measures of cardiovascular reactivity...Ch. 3 - The data set in Table 3.12 is based on 214...Ch. 3 - The data set in Table 3.12 is based on 214...Ch. 3 - The data set in Table 3.12 is based on 214...Ch. 3 - A drug company is developing a new pregnancy-test...Ch. 3 - A drug company is developing a new pregnancy-test...Ch. 3 - A drug company is developing a new pregnancy-test...Ch. 3 - Gynecology A drug company is developing a new...Ch. 3 - The Chinese Mini-Mental Status Test (CMMS)...Ch. 3 - The Chinese Mini-Mental Status Test (CMMS)...Ch. 3 - Mental Health The Chinese Mini-Mental Status Test...Ch. 3 - Construct an ROC curve based on the table...Ch. 3 - Mental Health The Chinese Mini-Mental Status Test...Ch. 3 - Calculate the area under the ROC curve. Interpret...Ch. 3 - Demography A study based on data collected from...Ch. 3 - Prob. 94PCh. 3 - Demography A study based on data collected from...Ch. 3 - Demography A study based on data collected from...Ch. 3 - Prob. 97PCh. 3 - The 4 allele of the gene encoding apolipoprotein E...Ch. 3 - Mental Health The 4 allele of the gene encoding...Ch. 3 - Mental Health The 4 allele of the gene encoding...Ch. 3 - Cardiovascular Disease A fascinating subject of...Ch. 3 - Cardiovascular Disease A fascinating subject of...Ch. 3 - Are these proportions prevalence rates, incidence...Ch. 3 - Prob. 104PCh. 3 - A dominantly inherited genetic disease is...Ch. 3 - A dominantly inherited genetic disease is...Ch. 3 - Prob. 107PCh. 3 - Infectious Disease, Cardiovascular Disease A...Ch. 3 - Infectious Disease, Cardiovascular Disease A...Ch. 3 - Infectious Disease, Cardiovascular Disease A...Ch. 3 - Prob. 114PCh. 3 - Genetics Suppose a birth defect has a recessive...Ch. 3 - A further study finds that after 10 generations...Ch. 3 - A further study finds that after 10 generations...Ch. 3 - Orthopedics Piriformis syndrome is a pelvic...Ch. 3 - Prob. 119PCh. 3 - Orthopedics Piriformis syndrome is a pelvic...Ch. 3 - Prob. 121PCh. 3 - Cancer Breast cancer is considered largely a...Ch. 3 - Cancer Breast cancer is considered largely a...Ch. 3 - Cancer Breast cancer is considered largely a...Ch. 3 - Prob. 125PCh. 3 - Cardiovascular Disease Mayo Clinic investigators...Ch. 3 - Prob. 127PCh. 3 - Prob. 128PCh. 3 - Prob. 129PCh. 3 - Prob. 130PCh. 3 - Prob. 131PCh. 3 - Prob. 132PCh. 3 - Radiology Mobile displays have the potential to...Ch. 3 - Radiology Mobile displays have the potential to...Ch. 3 - Prob. 135PCh. 3 - Prob. 136PCh. 3 - Prob. 137PCh. 3 - Cardiovascular Disease The ankle-arm...Ch. 3 - Cardiovascular Disease The ankle-arm...Ch. 3 - Cardiovascular Disease The ankle-arm...Ch. 3 - Prob. 141PCh. 3 - Prob. 142PCh. 3 - Prob. 143PCh. 3 - Obstetrics, Health Promotion A study was performed...
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