EBK FUNDAMENTALS OF BIOSTATISTICS
8th Edition
ISBN: 9781305465510
Author: Rosner
Publisher: YUZU
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Chapter 3, Problem 28P
Commonly used vaccines for influenza are trivalent and contain only one type of influenza B virus. They may be ineffective against other types of influenza B virus. A randomized clinical trial was performed among children 3 to 8 years of age in 8 countries. Children received either a quadrivalent vaccine (QIV) that had more than one influenza B virus or a trivalent Hepatitis A vaccine (control) (Jain, et al., [9]. New England Journal of Medicine 2013: 369(26): 2481–2491). An attack rate (i.e.,% of children who developed influenza) starting 14 days after vaccination until the end of the study was computed for each vaccine group, stratified by age. The following data were reported:
Table 3.7 Attack rate for influenza by age and treatment group
Suppose 3 children in a village ages 3, 5, and 7 are vaccinated with the QIV vaccine. What is the
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Chapter 3 Solutions
EBK FUNDAMENTALS OF BIOSTATISTICS
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