Infectious Disease, Cardiovascular Disease A validation study is to be performed in a local hospital to check the accuracy of assessment of hospital-acquired infection (INF) following coronary bypass surgery (coronary-artery bypass graft, or CABG). In a given year the hospital performs 1100 CABG procedures. A Centers for Disease Control and Prevention (CDC) algorithm is currently used to categorize subjects as having INF. To validate this algorithm, all CDC + subjects ( N = 100) and a random sample of CDC − subjects ( N = 1000) will be ascertained by an infectious-disease (ID) fellow and a detailed investigation will be performed, including a chart review and documentation of antibiotic use. Assume the ID-fellow’s determination is correct. Suppose 100 CDC + subjects are ascertained, of whom the ID fellow confirms 80. Because there are a large number of CDC − subjects (1000), only a sample of 100 is studied, of whom the ID fellow confirms 90. What is the PV + of the CDC algorithm?
Infectious Disease, Cardiovascular Disease A validation study is to be performed in a local hospital to check the accuracy of assessment of hospital-acquired infection (INF) following coronary bypass surgery (coronary-artery bypass graft, or CABG). In a given year the hospital performs 1100 CABG procedures. A Centers for Disease Control and Prevention (CDC) algorithm is currently used to categorize subjects as having INF. To validate this algorithm, all CDC + subjects ( N = 100) and a random sample of CDC − subjects ( N = 1000) will be ascertained by an infectious-disease (ID) fellow and a detailed investigation will be performed, including a chart review and documentation of antibiotic use. Assume the ID-fellow’s determination is correct. Suppose 100 CDC + subjects are ascertained, of whom the ID fellow confirms 80. Because there are a large number of CDC − subjects (1000), only a sample of 100 is studied, of whom the ID fellow confirms 90. What is the PV + of the CDC algorithm?
A validation study is to be performed in a local hospital to check the accuracy of assessment of hospital-acquired infection (INF) following coronary bypass surgery (coronary-artery bypass graft, or CABG). In a given year the hospital performs 1100 CABG procedures. A Centers for Disease Control and Prevention (CDC) algorithm is currently used to categorize subjects as having INF. To validate this algorithm, all CDC+ subjects (N = 100) and a random sample of CDC− subjects (N = 1000) will be ascertained by an infectious-disease (ID) fellow and a detailed investigation will be performed, including a chart review and documentation of antibiotic use. Assume the ID-fellow’s determination is correct.
Suppose 100 CDC+ subjects are ascertained, of whom the ID fellow confirms 80. Because there are a large number of CDC− subjects (1000), only a sample of 100 is studied, of whom the ID fellow confirms 90.
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Part (b)
Draw a scatter plot of the ordered pairs.
N
Life
Expectancy
Life
Expectancy
80
70
600
50
40
30
20
10
Year of
1950
1970 1990
2010 Birth
O
Life
Expectancy
Part (c)
800
70
60
50
40
30
20
10
1950
1970 1990
W
ALT
林
$
#
4
R
J7
Year of
2010 Birth
F6
4+
80
70
60
50
40
30
20
10
Year of
1950 1970 1990
2010 Birth
Life
Expectancy
Ox
800
70
60
50
40
30
20
10
Year of
1950 1970 1990 2010 Birth
hp
P.B.
KA
&
7
80
% 5
H
A
B
F10
711
N
M
K
744
PRT SC
ALT
CTRL
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