Biochemistry
6th Edition
ISBN: 9781305577206
Author: Reginald H. Garrett, Charles M. Grisham
Publisher: Cengage Learning
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Chapter 29, Problem 17P
Interpretation Introduction
Interpretation:
To determine the reason for the position of a-amanitin to be consistent with its inhibition modes.
Concept introduction:
DNA or Deoxyribonucleic acid is a molecule made of two chains which coil around one another. These form a double helix which carries instructions genetical in nature like related to reproduction, growth, development, functioning of the living organisms.
a-amanitin inhibits RNA polymerase II. This toxin which slows the polymerase translocation along DNA for NTP substrates has no effect on enzyme’s affinity.
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1 it is written tranlation and trancription occurs early in bacteria does that means in bacteria central dogma rule dosen't follow
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Different sensitivities to the mushroom toxin a-amanitin distinguish the three RNA polymerases from one another. Which of the following properties listed below also distinguish RNA Polymerase II from Pol I and Pol III?
Options:
Only RNA Pol II possesses a large subunit
RNA Polymerase I and RNA Polymerase III do not require TBP for optimal transcription efficiency
only RNA Polymerase II requires an ATP-dependent helicase to melt the DNA around the transcription start site
Only RNA Polymerase II resembles the prokaryotic RNA Polymerase
RNA Pol II has an extended N terminal region that becomes phosphorylated during intiation
Chapter 29 Solutions
Biochemistry
Ch. 29 - Prob. 1PCh. 29 - The Events in Transcription Initiation Describe...Ch. 29 - Substrate Binding by RNA Polymerase RNA polymerase...Ch. 29 - Comparison of Prokaryotic and Eukaryotic...Ch. 29 - Prob. 5PCh. 29 - Prob. 6PCh. 29 - Prob. 7PCh. 29 - Alternative Splicing Possibilities Suppose exon 17...Ch. 29 - Prob. 9PCh. 29 - Prob. 10P
Ch. 29 - Post-transcriptional Modification of Eukaryotic...Ch. 29 - Prob. 12PCh. 29 - Prob. 13PCh. 29 - The Lariat Intermediate in RNA Splicing Draw the...Ch. 29 - Prob. 15PCh. 29 - Prob. 16PCh. 29 - Prob. 17PCh. 29 - Prob. 18PCh. 29 - Figure 29.15 highlights in red the DNA phosphate...Ch. 29 - Chromatin decompaction is a preliminary step in...
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