Biochemistry
Biochemistry
6th Edition
ISBN: 9781305577206
Author: Reginald H. Garrett, Charles M. Grisham
Publisher: Cengage Learning
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Chapter 29, Problem 11P

Post-transcriptional Modification of Eukaryotic mRNAs What might be the advantages of capping, methylation, and polyadenylylation of eukaryotic mRNAs?

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Introns in protein-coding genes of some eukaryotes are rarely shorter than 65 nucleotides long. What might be a rationale for this limitation?
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Keeping in mind the three main processing events that occur in eukaryotes (5' capping, 3' cleavage and intron splicing) would it be reasonable to conclude that the mature RNA would contains exons, a promoter region (to the left of the transcription site) and a poly A tail?
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