B- Vitamins are converted readily into important metabolic cofactors. Deficiency inany one of them has serious side effects. a. The disease beriberi results from a vitamin B 1 (Thiamine) deficiency and ischaracterized by cardiac and neurological symptoms. One key diagnostic forthis disease is an increased level of pyruvate and α-ketoglutarate in thebloodstream. How does this vitamin deficiency lead to increased serumlevels of these factors? b. What would you expect the effect on the TCA intermediates for a patientsuffering from vitamin B 5 deficiency? c. What would you expect the effect on the TCA intermediates for a patientsuffering from vitamin B 2 /B 3 deficiency?
B- Vitamins are converted readily into important metabolic cofactors. Deficiency inany one of them has serious side effects. a. The disease beriberi results from a vitamin B 1 (Thiamine) deficiency and ischaracterized by cardiac and neurological symptoms. One key diagnostic forthis disease is an increased level of pyruvate and α-ketoglutarate in thebloodstream. How does this vitamin deficiency lead to increased serumlevels of these factors? b. What would you expect the effect on the TCA intermediates for a patientsuffering from vitamin B 5 deficiency? c. What would you expect the effect on the TCA intermediates for a patientsuffering from vitamin B 2 /B 3 deficiency?
Human Physiology: From Cells to Systems (MindTap Course List)
9th Edition
ISBN:9781285866932
Author:Lauralee Sherwood
Publisher:Lauralee Sherwood
Chapter19: The Peripheral Endocrine Glands
Section: Chapter Questions
Problem 5TAHL
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B- Vitamins are converted readily into important metabolic cofactors. Deficiency in
any one of them has serious side effects.
a. The disease beriberi results from a vitamin B 1 (Thiamine) deficiency and is
characterized by cardiac and neurological symptoms. One key diagnostic for
this disease is an increased level of pyruvate and α-ketoglutarate in the
bloodstream. How does this vitamin deficiency lead to increased serum
levels of these factors?
b. What would you expect the effect on the TCA intermediates for a patient
suffering from vitamin B 5 deficiency?
c. What would you expect the effect on the TCA intermediates for a patient
suffering from vitamin B 2 /B 3 deficiency?
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