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The peptide Leu-Cys-Arg-Ser-Gln-Met is subjected to Edman degradation. In the first cycle the peptide first reacts with phenylisothiocyanate under basic conditions. The product of this reaction is incubated with anhydrous trifluoroacetic acid and subsequently with an aqueous acid. What are the products generated in the first cycle. PTH-Leu, PTH-Cys, PTH-Arg, PTH-Ser, PTH-Gln, and PTH-Met PTH-Leu-Cys-Arg-Ser-Gln-Met PTH-Met and Leu-Cys-Arg-Ser-Gln-Met PTH-Leu-Cys and PTH-Arg-Ser-Gln-Met PTH-Leu and Cys-Arg-Ser-Gln-Met

The peptide Leu-Cys-Arg-Ser-Gln-Met is subjected to Edman degradation. In the first cycle the peptide first reacts with phenylisothiocyanate under basic conditions. The product of this reaction is incubated with anhydrous trifluoroacetic acid and subsequently with an aqueous acid. What are the products generated in the first cycle. PTH-Leu, PTH-Cys, PTH-Arg, PTH-Ser, PTH-Gln, and PTH-Met PTH-Leu-Cys-Arg-Ser-Gln-Met PTH-Met and Leu-Cys-Arg-Ser-Gln-Met PTH-Leu-Cys and PTH-Arg-Ser-Gln-Met PTH-Leu and Cys-Arg-Ser-Gln-Met

Biochemistry
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
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The peptide Leu-Cys-Arg-Ser-Gln-Met is subjected to Edman degradation. In the first cycle the peptide first reacts with phenylisothiocyanate under basic conditions. The product of this reaction is incubated with anhydrous trifluoroacetic acid and subsequently with an aqueous acid. What are the products generated in the first cycle. PTH-Leu, PTH-Cys, PTH-Arg, PTH-Ser, PTH-Gln, and PTH-Met PTH-Leu-Cys-Arg-Ser-Gln-Met PTH-Met and Leu-Cys-Arg-Ser-Gln-Met PTH-Leu-Cys and PTH-Arg-Ser-Gln-Met PTH-Leu and Cys-Arg-Ser-Gln-Met
Transcribed Image Text:The peptide Leu-Cys-Arg-Ser-Gln-Met is subjected to Edman degradation. In the first cycle the peptide first reacts with phenylisothiocyanate under basic conditions. The product of this reaction is incubated with anhydrous trifluoroacetic acid and subsequently with an aqueous acid. What are the products generated in the first cycle. PTH-Leu, PTH-Cys, PTH-Arg, PTH-Ser, PTH-Gln, and PTH-Met PTH-Leu-Cys-Arg-Ser-Gln-Met PTH-Met and Leu-Cys-Arg-Ser-Gln-Met PTH-Leu-Cys and PTH-Arg-Ser-Gln-Met PTH-Leu and Cys-Arg-Ser-Gln-Met
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