how to calculate if a drug is eliminated by zero order or first order kinetics given a table of plasma concentration versus time
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how to calculate if a drug is eliminated by zero order or first order kinetics given a table of plasma concentration versus time
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- Compute for the loading dose of Gentamicin for a 135-pound patient if the target plasma concentration is 0.06mg/L. The hypothetical volume of distribution of the drug is 0.36L/kg body weightHow much active ingredient in 20 cc of a 15% solution? You have 1:1000 concentration of epinephrine. How many mLs do you need to draw up if you want to give 45 mg of the drug? (I need help please :)Answer in text with explanation and summary
- Give typed solution only Calculate the ML/HR (rate) Merrem 1 g (1g/50 mL of 0.9% NACL) IVBP Q 12 hours Infuse over 30 minutes. *Please show how you would work this using dimensional analysis, if possible. If not, it's fine if you show how you arrived at your answer another way*Calculate the oral loading dose (LD) of digoxin for Miss Jones who weighs 60 kg. The desired plasma concentration (Cp) is 1.5 mcg/L, volume of distribution (Vd) is 7.3 L/kg, the salt factor (S) is 1 and bioavailability fraction (F) is 0.7.Give your answer to the nearest whole number of micrograms.The equation below can be used:Loading Dose = Cp desired x VdS x FA glucose solution is supplied in a repeated fed batch culture. The following parameters have been measured at t=2.5 hours; the system was under a quasi-steady state at this time. V = 1.0L, F = 0.22L/hr, S_0 = 98g/L, mu_m = 0.31/hr, K_s = 0.14 g-glucose/L, YM_X/S = 0.48 g-cells/g-glucose, Xt_0 = 33g (1) Calculate the value of V0 and S. (2) Calculate the value of Xt for t = 2.5hrs.
- Insulin Lispro subcutaneously for a patient weight 80 kg for 1 month of treatment. Daily dose of insulin is 1 Unit/kg and 60% in short acting, given 4 times per day; ampoules in form of personal injectors (300 Units/3ml). (I would like to figure out the number of personal injector needed for 1 month.) My answer: Daily dose (DD) for a 80 kg patient = 80 x 1 Unit = 80 U 60% is short acting, so DD = 60% of 80 U = (0.6 × 80) U = 48 U Given 4 times per day, so for a single dose = 48 U/4 = 12 U For 1 month (30 days), 30 x 48U = 1440 U Rp. Insulin lispro in ampoules personal injectors 300 Units/3 ml No. ??? (my teacher write is 10 but I don't understand why) Sig. Inject subcutaneously 12 Unit (0.12 ml) before each meal, 4 times a day for 1 month.In the preparation of an intravenous infusion, a vial containing 100 mg of drug is diluted to 2 mL with sodium chloride for injection. Then, the contents of the vial are added to 100 mL of an infusion solution. Calculate the final strength of the drug infusion in percentage strength (% w/v)252F%252Fbbniagaraccc.sin.suny.edu%252Fwebapps signment Saved He One of the uses of diazepam is as an antiepileptic that can be administered by slow IV infusion at a rate of 0.5 mg/min for 1 hour. If the infusion solution consists of 6 ml and there are 15 drops per milliliter of solution, how many drops per minute should be administered? drops per minute
- The erythrocyte sedimentation rate (heaviness) test of a blood sample is often used as a diagnosis of immune disorders and some other diseases. Assuming that the red blood cells are about a sphere with a diameter of (approximately 5 um) and a density (g/ml 1.125), and the density and viscosity of the plasma in which the red blood cells are settled (Pa.s), (1025 kg/m3 10-3 x 1.5) On arrangement and acceleration m/s2 9.81 Calculate the erythrocyte sedimentation rate (settlement rate).The effect of pressure on flow rate Set-up: For investigating the effect of pressure (height of a column of liquid), a 50-mL burette was used with a small length of rubber tubing fixed to the bottom on which a clamp could be fitted to start/stop the flow of water (Figure 1). Effluent was collected in a beaker and mean flow rate was calculated (mL/s), and a stopwatch was used to measure how long it took for 5 mL of liquid to flow out. For the subsequent sections of the practical, a 25-mL burette was used, and the top was connected via rubber tubing to a 5-liter reservoir placed on the shelving above the bench. The tubing at the base was connected to the different flow modules that comprised the different configurations of tubes to be tested. Interpret the graph. What does this relate to in the cardiovascular system, and is it something that can change? How? What would be the implications for our ability to control blood flow to different tissues, if this were the only control mechanism…situations that would cause blockage in the circulation of blood in animals and blockage in the transport of necessary materials in plants. Have them write possible solutions for this?
