FUND.OF GEN CHEM CHAP 1-13 W/ACCESS
FUND.OF GEN CHEM CHAP 1-13 W/ACCESS
16th Edition
ISBN: 9781323406038
Author: McMurry
Publisher: PEARSON C
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Chapter 28, Problem 28.30AP
Interpretation Introduction

Interpretation:

The three major classes of hormones have to be determined.

Concept Introduction:

Amino acids: Amino acids are compounds having both NH2 and COOH groups in the specific alkyl chain corresponding to the each amino acid.

Hormones: Hormones are chemical messengers which are secreted by the cell in endocrine system and are transported along the blood to stimulate the target cells having the corresponding receptors.

Hormones are of three types,

  1. 1. Amino acid derivatives: It is a derivative of an amino acid formed by the reaction at the side chain functional group, carboxylic acid group, amino group or by the replacement of a hydrogen atom by heteroatom.
  2. 2. Polypeptides: Polypeptides are organic polymers having several amino acids attached to each other in a chain.
  3. 3. Steroid: Steroids are a type of organic compound having a molecular structure with four rings connected to each other.

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To map the active site of beta-lactamase, the enzyme was hydrolyzed with trypsin to yield a hexapeptide (P1) with the following amino acids. Glu, Lys, Leu, Phe, Met, and Ser. Treatment of P1 with phenyl isothiocyanate yielded a PTH derivative of phenylalanine and a peptide (P2). Treatment of P1 with cyanogenbromide gave an acidic tetrapeptide (P3) and a dipeptide (P4).Treatment of P2 with 1-fluoro-2,4-dinitrobenzene, followed by complete hydrolysis, yields N-2,4-dinitrophenyl-Glu. P1, P2, and P3 contain the active site serine. Why doesn't D in this hexapeptide not participate in the hydrolysis of the beta-lactam ring even though S, K, and D are involved in the catalyst?
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Chapter 28 Solutions

FUND.OF GEN CHEM CHAP 1-13 W/ACCESS

Ch. 28.4 - Prob. 28.9PCh. 28.5 - Prob. 25.10PCh. 28.6 - Prob. 28.11PCh. 28.6 - Prob. 28.12PCh. 28.6 - Prob. 28.13KCPCh. 28.7 - Identify the functional groups present in THC. Is...Ch. 28.7 - Prob. 28.15KCPCh. 28 - Prob. 28.16UKCCh. 28 - Prob. 28.17UKCCh. 28 - Prob. 28.18UKCCh. 28 - Prob. 28.19UKCCh. 28 - Prob. 28.20UKCCh. 28 - Prob. 28.21UKCCh. 28 - Prob. 28.22APCh. 28 - Prob. 28.23APCh. 28 - Prob. 28.24APCh. 28 - Prob. 28.25APCh. 28 - Prob. 28.26APCh. 28 - Prob. 28.27APCh. 28 - Prob. 28.28APCh. 28 - Prob. 28.29APCh. 28 - Prob. 28.30APCh. 28 - Prob. 28.31APCh. 28 - Prob. 28.32APCh. 28 - Prob. 28.34APCh. 28 - Prob. 28.35APCh. 28 - Prob. 28.36APCh. 28 - Prob. 28.37APCh. 28 - How does epinephrine reach its target tissues?Ch. 28 - Prob. 28.39APCh. 28 - Prob. 28.40APCh. 28 - Prob. 28.41APCh. 28 - Prob. 28.42APCh. 28 - What enzyme catalyzes hydrolysis of the second...Ch. 28 - Prob. 28.44APCh. 28 - Prob. 28.45APCh. 28 - Prob. 28.46APCh. 28 - Prob. 28.47APCh. 28 - Prob. 28.48APCh. 28 - Prob. 28.49APCh. 28 - Prob. 28.50APCh. 28 - Prob. 28.51APCh. 28 - Prob. 28.52APCh. 28 - Prob. 28.53APCh. 28 - Prob. 28.54APCh. 28 - Prob. 28.55APCh. 28 - Prob. 28.56APCh. 28 - Prob. 28.57APCh. 28 - Prob. 28.58APCh. 28 - Prob. 28.59APCh. 28 - Prob. 28.60APCh. 28 - Prob. 28.62APCh. 28 - Prob. 28.63APCh. 28 - Prob. 28.64APCh. 28 - Prob. 28.65APCh. 28 - Prob. 28.66APCh. 28 - Prob. 28.67APCh. 28 - Prob. 28.68APCh. 28 - Prob. 28.69APCh. 28 - Prob. 28.70APCh. 28 - Prob. 28.71APCh. 28 - Prob. 28.72APCh. 28 - Prob. 28.73APCh. 28 - Prob. 28.74APCh. 28 - Prob. 28.75APCh. 28 - Prob. 28.76APCh. 28 - Why do we have brain receptors that respond to...Ch. 28 - Prob. 28.78APCh. 28 - Prob. 28.79APCh. 28 - Prob. 28.80APCh. 28 - Prob. 28.81APCh. 28 - Prob. 28.82APCh. 28 - Prob. 28.83CPCh. 28 - Prob. 28.84CPCh. 28 - Prob. 28.85CPCh. 28 - Prob. 28.86CPCh. 28 - Prob. 28.87CPCh. 28 - Prob. 28.88CPCh. 28 - Prob. 28.89CPCh. 28 - Prob. 28.90CPCh. 28 - Prob. 28.91CPCh. 28 - Prob. 28.92CPCh. 28 - Prob. 28.93CPCh. 28 - Prob. 28.94GPCh. 28 - Prob. 28.95GP
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