Concept explainers
Interpretation:
It should be determined that how the given stimulants (Caffeine and theobromine) might interact with an enzyme in the cAMP pathway to enhance the effect of cAMP.
Concept introduction:
Stimulants: These are a group of drugs with many potential therapeutic uses, but also widely used and abused recreationally. Stimulants improve mood, enhance alertness and relieve depression.
Caffeine, Nicotine, Cocaine, Ecstasy … are some examples for stimulants.
cAMP is a cyclic
Enzymes are proteins that increase the
Secondary messengers are short lived intracellular signaling molecules. Elevated concentration of these type of messengers leads to rapid alteration in the activity of one or more cellular enzymes.
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FUND.OF GEN CHEM CHAP 1-13 W/ACCESS
- 3. Identify carbons 3 and 5 in the monosaccharides below H H H H OH 0 H 0 CH₂OH H CH₂OH OH H 0 H CH₂OH о H H H OH OH H OH H OH OH OH H OH OH H OH OH OH CH₂OH 1 H H H Harrow_forwardApply your knowledge Why are monosaccharides highly soluble in water? Why do monosaccharides have high boiling and melting points? Identify carbons 3 and 5 in the monosaccharides below 9 Reducing & non - reducing sugars ( Learning goal 5) A classification that helps differentiate monosaccharides Reducing sugars Also known as aldoses. E. g. glucose Changes Benedicts solution from ) blue to redarrow_forwardBook problem 28-22: Human and horse insulin both have two polypeptide chains, with one chain containing 21 amino acids and the other containing 30 amino acids. They differ in primary structure at two places. At position 9 in one chain, human insulin has Ser and horse insulin has Gly; at position 30 in the other chain, human insulin has Thr and horse insulin has Ala. How must the DNA for the two insulins differ? Book problem 28-24: The codon UAA stops protein synthesis. Why does the sequence UAA in the following stretch of mRNA not cause any problems? Provide a 1-2 sentence response. -GCA-UUC-GAG-GUA-ACG-CCC- For what amino acids do the following ribonucleotide triplets code?arrow_forward
- How might valganciclovir interfere with dna synthesisarrow_forwardA. Piefly summarize the process of transcription. Include in your summary a list of at least 2 proteins that are involved in transcription. Your summary should be 2-3 sentences long. B. Pyrrole-imidazole polyamides such as the ones discussed in this paper are designed to bind specific sites on DNA. These types of polyamides can be used to inhibit transcription. a. Explain in 1-2 sentences how a molecule that binds to a specific DNA sequence could inhibit transcription. b. Many types of cancer are caused by problems with transcription. Explain in 1-2 sentences why a molecule like a polyamide would be better for treating a cancer caused by mis-regulations in transcription than a molecule that inhibits the functionality of RNA polymerase II. (Hint, think about side effects). C. A chemist made a similar molecule but rather than using pyrroles and imidazoles, they just used cyclopentane molecules. Would this molecule bind DNA as efficiently as the original polyamide? Explain your answer in…arrow_forwardExplain #8 a&b thoroughly. DRAW the structures below (neatly, please): a. an ionic bond between Asp and Arg side chainsb. hydrophobic interactions between Trp and Val side chainsarrow_forward
- Explain question #6 thoroughly. In an aqueous environment will the following peptide fragment more likely be buried inside a globular protein or on its surface? Explain.arrow_forwardA lack of the enzyme glucose 6-phosphatase is one of the causes of the glycogen storage disorder von Gierke disease. Predict three signs or symptoms of von Gierke disease. hyperlipidemia (high lipid concentration in blood) normal glycogen structure, with very large amounts present in liver cirrhosis of the liver increased amounts of lactate and pyruvate in blood muscle crampsarrow_forwardShow work with explanation needed. Don't give Ai generated solutionarrow_forward
- Draw the structure of 2, 2-diiodobutane and convert this achiral compound to chiral compound by changing ONLY 1 atom in the structure. Name the new compound.arrow_forwardIdentify the chiral carbon atoms in each structure. If no chiral carbon atoms are present write: "None present". a) 1 2 3 4 LO 6 b) 8 10 7 CI 9 7 6 5 4 13 CI 2 1arrow_forwardHOCH2 HOCH2 OH OH OCH3 OCH 3 OH OH 1) Is this structure a monosaccharide or disaccharide or trisaccharide? 2) What is the molecular formula of this structure? 3) Is this compound soluble in water? 4) What type of sugars are present (D or L)? Explainarrow_forward
- Human Physiology: From Cells to Systems (MindTap ...BiologyISBN:9781285866932Author:Lauralee SherwoodPublisher:Cengage Learning