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Concept explainers
Interpretation:
The name of three drug families which are used to treat depression has to be listed.
Concept Introduction:
Neurotransmitters: Neurotransmitters are chemicals that transmit messages from the nervous system to the target cell. They are the chemical messagers where the electrical signal from the nervous system is travelled from one neuron to another to reach the target cell.
The “big three” neuro transmitters are serotonin, norepinephrine and dopamine and are also called monoamines. The deficiency of the neurotransmitters serotonin, norepinephrine and dopamine leads to depression.
By the mode of action, three families of drugs are used as effective anti-depressant. They are Tricyclic antidepressant (Elavil), Monoamine oxidase (MAO) inhibitor (Nardil) and Selective serotonin re-uptake inhibitors, SSRI (Prozac)
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Chapter 28 Solutions
FUND.OF GEN CHEM CHAP 1-13 W/ACCESS
- 3. (15 points) Living cells homogeneously distributed (immobilized) with an agarose gel require glucose to survive. An important aspect of the biochemical system design is the effective diffusion coefficient of glucose (A) into the cell- immobilized gel. Consider the experiment shows below where a slab of the cell-immobilized gel of 1.0cm thickness is placed within a well-mixed aqueous solution of glucose maintained at a concentration of 50 mmol/L. The glucose consumption within the cell-immobilized gel proceeds by a zero-order process given by R₁ = -0.05 mmol/(L min). The solubilities of glucose in both the water and the gel are the same; that is, the concentration of the glucose on the water side of the water-gel interface is equal to the concentration of the glucose on the gel side of the water gel interface. A syringe is mounted at the center of the gel carefully excises a tiny sample of the gel for glucose analysis. A Well mixed solution Constant concentration 50nmol/L Living…arrow_forwardTwo tetrapeptides were isolated from a possum's sweat glands. These peptides were sequenced using Edman degradation and the following 2 sequences were obtained: Gly-Asp-Ala-Leu Gly-Asp-Asp-Leu Can you please help show the titration curve for both of these peptides and calculate the PI?arrow_forwardTwo tetrapeptides were isolated from a possum's sweat glands. These peptides were sequenced using Edman degradation and the following 2 sequences were obtained: Gly-Asp-Ala-Leu Gly-Asp-Asp-Leu What is the structure of the PTH derivative produced during the last round of amino acid sequencing?arrow_forward
- What is the primary sequence of this undecapeptide? Also, if x-ray crystallography shows a highly stable hairpin turn within the polypeptide, what about the primary sequence explains this structural feature?arrow_forwardDraw the product of this reaction. Ignore inorganic byproducts. H H ⚫OH HO- -H H- -OH H- -OH CH2OH Ag*, NH4OH, H2O Draw Fischer Projectionarrow_forwardDraw the product of this reaction. Ignore inorganic byproducts. H₂O -OH H ⚫OH HO H HO- CH2OH Cu2+ Draw Fischer Projectionarrow_forward
- Draw the product of this reaction. Ignore inorganic byproducts. H、 H -OH H ⚫OH H -OH CH2OH Fehlings' solution ⑤ Draw Fischer Projectionarrow_forwardDraw the product of this reaction. Ignore inorganic byproducts. HO C=0 H ⚫OH H ⚫OH HO- H HO H CH2OH Tollens' solution Draw Fischer Projectionarrow_forwardDraw the product of this reaction. Ignore inorganic byproducts. H-C=O HO H HO H H- ⚫OH HO H CH2OH HNO3, H2O Draw Fischer Projectionarrow_forward
- Draw the product of this reaction. Ignore inorganic byproducts. HO HO- HO H HO ∙H HO CH2OH NaBH4, CH3OH Draw Fischer Projectionarrow_forwardDraw the product of this reaction. Ignore inorganic byproducts. Но сво HO H HO H H OH H -OH CH2OH H2 Pd Draw Fischer Projectionarrow_forwardDraw the Haworth projection for Gulose-ẞ-1,6-sorbose and answer the following questions. (Gulose will be in the pyranose form and Sorbose will be in the furanose form) a. Label the reducing and nonreducing ends of the disaccharide b. Label the glycosidic bond c. Circle the anomeric carbons and label them as hemiacetals or acetals. d. Can this disaccharide undergo mutarotation?arrow_forward
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