Concept explainers
Interpretation:
The small differences in the structures of cholesterol and cholate have to be identified. It should be determined that whether the roles of these molecules be reversed or not.
Concept introduction:
Cholesterol: it is a soft, fat-like, waxy substance found in the blood stream and all our body’s cells. It is an essential component of mammalian cell membranes where it is required to establish proper membrane permeability and fluidity. It is the principal sterol synthesized by animals.
Cholate is a salt or ester of cholic acid. It is associated with choleic acid in the bile
Sterols are steroid alcohol which is occurring naturally in plants, animals and in
Want to see the full answer?
Check out a sample textbook solutionChapter 24 Solutions
FUND.OF GEN CHEM CHAP 1-13 W/ACCESS
- What are the three stages required for the synthesis of cholesterol?arrow_forwardwhy is chymotrypsin inactive at high pH?arrow_forwardH CH₂ H₂C HC-CH3 CH₂ H H₂C (S) H₂C H CH₂ CH₂ CH₂ NH O C NH NH₂ a) Which of the following statements about this peptide are correct? Group of answer choices Treatment of this peptide with trypsin generates two products. This peptide is a substrate for carboxypeptidase A Treatment of this peptide with cyanogen bromide generates a pentapeptide and a tripeptide. Treatment of this peptide with chymotrypsin generates three products. Treatment of this peptide with elastase generates 2 products. None of the above statements are correct. b) What is the sequence of this peptide using one letter abbreviations? c) What is the pH which would correspond to the ionization of the peptide as drawn above? 1, 5, 7, 10, 14arrow_forward
- Individuals with phenylketonuria (PKU) are sensitive to phenylalanine in their diet. Why is a warning on foods containing aspartame (L-aspartyl-l-phenylalanine methyl ester) of concern to individuals with PKU?arrow_forwardThe peptide CMYLES is reacted with phenylisothiocyanate under basic conditions followed by incubation with anhydrous trifluoroacetic acid. What are the products of this reaction? PTH-CMYLES Thiazolinone derivative of cysteine, MYLES O PTH-C, PTH-M, PTH-Y, PTH-L, PTH-E, PTH-S PTH-C, MYLES PTH-S, CMYLEarrow_forwardthe following peptide is incubated as chymotrypsin: Gly-Val-Phe-Lys-Ala. Present the detailed chemical mechanism by which chymotrypsin hydrolyzes this peptide. Briefly explain each step. Include only the structure of the final products of the reaction.arrow_forward
- Chondroitin sulfate chains have been likened to a large fishnet, allowing small molecules to pass through but excluding large ones. What structural features of chondroitin sulfate and proteoglycans in general are responsible for this phenomenon?arrow_forwardAbout cardiotonic glycosides, based on a digoxin structure in the image: Classify the α,β-unsaturated lactone present in digoxin. What is the mechanism of the pharmacological action of digoxin, explain in detail?arrow_forwardThe hexapeptide Ala-Met-Leu-Lys-Phe-Asp is digested in the same tube with both Cyanogen Bromide and Trypsin at the same time at pH=7. Draw the structure of the product(s) that would bind to a cation exchange column. (Relevant pKa values are 2.2, 3.9, 9.5 and 10.5. Assume pKa values for any newly generated a-amino and a-carboxyl groups are 9.5 and 2.2 respectively)arrow_forward
- Human Heredity: Principles and Issues (MindTap Co...BiologyISBN:9781305251052Author:Michael CummingsPublisher:Cengage Learning