For a red blood cell (erythrocyte) undergoing active glycolysis, briefly explain howincreases in concentration of the following factors are likely to affect glycolytic flux.a. ATPb. AMPc. F-1,6-BPd. F-2,6-BPe. Citratef. Glucose-6-phosphate

The glycolytic flux in red blood cells (RBCs) is regulated by various factors through allosteric…

Answered: For a red blood cell (erythrocyte)…

Concepts of Biology

1st Edition

ISBN:9781938168116

Author:Samantha Fowler, Rebecca Roush, James Wise

Publisher:Samantha Fowler, Rebecca Roush, James Wise

Chapter4: How Cells Obtain Energy

Section: Chapter Questions

Problem 12RQ: The cholesterol synthesized by cells uses which component of the glycolytic pathway as a starting...

See similar textbooks

Similar questions

Understanding the Mechanism of Hemolytic Anemia Genetic defects in glycolytic enzymes can have serious consequences for humans For example, defects in the gene for pyruvate kinase can result in a condition known as hemolytic anemia. Consult a reference to learn about hemolytic anemia, and discuss why such genetic defects lead to this condition.
Study Figure 19.18 and decide which of the following statements is false. Pyruvate dehydrogenase is inhibited byÂ· NIADH. Pyruvate dehydrogenase is inhibited by AÎ¤Î¡. Citrate synthase is inhibited by NADH. Succinyl-CoA activates citrate synthase. Acetyl-CoA activates pyruvate carboxylase.
Characterizing Glycolysis List the reactions of glycolysis that a. are energy consuming (under standard-stale conditions), b. are energy yielding (under standard-state conditions), c. consume ATP. d. yield ATP e. are strongly influenced by changes in concentration of substrate and product because of their molecularity. f. are at or near equilibrium in the erythrocyte (see Table 18.2).
Using the answer code on the right, indicate which form of energy production is being described: 1. takes place in the mitochondrial matrix 2. produces H2O as a by-product 3. results in a rich yield of ATP 4. takes place in the cytosol 5. processes acetyl-CoA 6. takes place in the mitochondrial innermembrane cristae 7. converts glucose into two pyruvate molecules 8. uses molecular oxygen 9. accomplished by the electron transport system and ATP synthase (a) glycolysis (b) citric acid cycle (c) oxidative phosphorylation
Based on your residing of this chapter, what would you expect to be the most immediate effect oil glycolysis, if the steady-state concentration of gJucose-6-P were 8.3 mM instead of 0.083 mM?
Figure 27.3 illustrates the response of R (ATP-regenerating) and U (ATP-utilizing) enzymes to energy charge. a. Would hexokinase be an R enzyme or a U enzyme? Would glutamine: PRPP amidotransferase, the second enzyme in purine biosynthesis, be an R enzyme or a U enzyme? b. If energy charge = 0.5: Is the activity of hexokinase high or low? Is ribose-5-P pyrophosphokinase activity high or low? c. If energy charge = 0.95: Is the activity of hexokinase high or low? Is ribose-5-P pyrophosphokinase activity high or low?
Discuss the roles of phospholipase A2, cyclooxygenase, and lipooxygenase.
When muscle cells run out of oxygen, what happens to the potential for energy extraction from sugars and what pathways do the cell use?
The control of which enzyme exerts the most control on glycolysis? hexokinase phosphofructokinase glucose-6-phosphatase aldolase
The glucose that enters the glycolysis pathway is split into two molecules of _____. a. ATP b. phosphate c. NADH d. pyruvate
ATP for muscle contraction can be provided by ______. a. aerobic respiration b. lactate fermentation c. transfer of a phosphate from creatine phosphate d. all of the above
Based on your knowledge of the structure of NAD+ and an assumption that coenzyme dissociation is the rate limiting step of the alcohol dehydrogenase mechanism, hypothesize why a N249W mutation at the coenzyme binding site would increase the rate of catalysis.

SEE MORE QUESTIONS

Recommended textbooks for you

Concepts of Biology

Biology

ISBN:

9781938168116

Author:

Samantha Fowler, Rebecca Roush, James Wise

Publisher:

OpenStax College

Biochemistry

ISBN:

9781305577206

Author:

Reginald H. Garrett, Charles M. Grisham

Publisher:

Cengage Learning

Curren'S Math For Meds: Dosages & Sol

Nursing

ISBN:

9781305143531

Author:

CURREN

Publisher:

Cengage

Concepts of Biology

Biology

ISBN:

9781938168116

Author:

Samantha Fowler, Rebecca Roush, James Wise

Publisher:

OpenStax College

Biochemistry

ISBN:

9781305577206

Author:

Reginald H. Garrett, Charles M. Grisham

Publisher:

Cengage Learning

Curren'S Math For Meds: Dosages & Sol

Nursing

ISBN:

9781305143531

Author:

CURREN

Publisher:

Cengage

Human Physiology: From Cells to Systems (MindTap …

Biology

ISBN:

9781285866932

Author:

Lauralee Sherwood

Publisher:

Cengage Learning

Basic Clinical Laboratory Techniques 6E

Biology

ISBN:

9781133893943

Author:

ESTRIDGE

Publisher:

Cengage

Essentials of Pharmacology for Health Professions

Nursing

ISBN:

9781305441620

Author:

WOODROW

Publisher:

Cengage

SEE MORE TEXTBOOKS

For a red blood cell (erythrocyte) undergoing active glycolysis, briefly explain how increases in concentration of the following factors are likely to affect glycolytic flux. a. ATP b. AMP c. F-1,6-BP d. F-2,6-BP e. Citrate f. Glucose-6-phosphate