Interpretation:
The difference between
Concept introduction:
Fatty acids are aliphatic mono-
The process of catabolism of fatty acids includes three major parts and they are,
Activation of fatty acid and its transport into mitochondria
Beta-oxidation
Electron transport chain
Fatty acids in the body are mostly oxidized by
Lipogenesis is the
Lipogenesis requires;
Synthesis of fatty acids and glycerol
Activation of fatty acids by CoA and glycerol by glycerokinase
The combination of activated fatty acids and activated glycerol to produce TAG (triacylglycerol)
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FUND.OF GEN CHEM CHAP 1-13 W/ACCESS
- The pentose phosphate pathway is quite active in adipose tissue. Why? Explain how this pathway complements lipogenesis with the use of an example (such as a person eating chocolate).arrow_forwardIdentify whether each of the following is involved in b-oxidation or fatty acid synthesis?(a) NAD+(b) Malonyl-ACParrow_forwardWhich of the following statements is/are TRUE about fatty acid activation before β-oxidation? I. The process consumes energy equivalent to two moles of ATP. II. The fatty acid is activated by ATP to give a fatty acyl-CoA.arrow_forward
- Show the first cycle of beta-oxidation of stearic acid. How many ATPs will be generated from the complete oxidation of this fatty acid?arrow_forwardFor each of the steps below, choose (A) if the step pertains to b-oxidation, (B) if the step pertains to fatty acid synthesis, or (C) if the step is common to both processes. ______ Acetyl CoA is produced as a product.______ Activation (the committed step of the process) requires ATP hydrolysis. ______ Accumulated acetyl CoA serves as a substrate.______ The length of fatty acid carbon chain is modified in the mitochondria. ______ ACP acts as the acyl carrier.arrow_forwardCompare and contrast the pathways of fatty-acid breakdown and biosynthesis. What features do these two pathways have in common? How do they differ?arrow_forward
- In adipose tissue, the pentose phosphate pathway is quite active. Why? With the use of an example, explain how this route aids lipogenesis (such as a person eating chocolate).arrow_forwardDefine beta-oxidation of fatty acids? Describe in detail three different steps of beta-oxidation of FAs.arrow_forwardWhich of the following statements is TRUE about fatty acid biosynthesis? Citrate carries malonyl CoA to the cytosol. O Acetyl ACP is the donor of the acetyl group. O NADPH is used as the reducing equivalent in the process. O The product detaches from the fatty acid synthase complex when the chain length is usually 18 carbons.arrow_forward
- Describe the oxidative and non oxidative phases of Pentose phosphate pathways discusss how the flux through the pathway would be prioritized in a cell/tissue needing to synthesize fatty acids?. (answer in short sentences)arrow_forwardConsider oleic acid (18:1∆9): 1. How many NADH will be produced from complete oxidation of this fatty acid? 2. How many FADH2 will be produced from complete oxidation of this fatty acid? 3. Total number of ATP produced from NADH in complete oxidation of oleic acid (exclude transport cost of the fatty acid)? 4. Total number of ATP produced from FADH2 in complete oxidation of oleic acid (exclude transport costs of the fatty acid)? Please provide how you got them.arrow_forwardIn the mitochondrion is a short-chain carnitineacyltransferase that can take acetyl groups from acetyl-CoA and transfer them to carnitine. How might this be related to lipid biosynthesis?arrow_forward
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