Where the fatty acid binding sites of albumin are located; their relative affinities should be discussed. Concept Introduction: Human serum albumin (HSA) is a plasma protein which is responsible for the transportation of fatty acids. HSA also binds wide range of drugs and involve in pharmacokinetics. Interactions between fatty acids and drug binding sites on albumin have been studied through high resolution structural information and crystallographic data. Albumin has 11 different binding sites. HAS carries around 0.1 − 2 moles of fatty acids per mole of albumin.

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Chapter 23, Problem 5P

Interpretation Introduction

Interpretation:

Where the fatty acid binding sites of albumin are located; their relative affinities should be discussed.

Concept Introduction:

Human serum albumin (HSA) is a plasma protein which is responsible for the transportation of fatty acids. HSA also binds wide range of drugs and involve in pharmacokinetics. Interactions between fatty acids and drug binding sites on albumin have been studied through high resolution structural information and crystallographic data. Albumin has 11 different binding sites. HAS carries around 0.1 − 2 moles of fatty acids per mole of albumin.

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