Introduction to General, Organic and Biochemistry
Introduction to General, Organic and Biochemistry
11th Edition
ISBN: 9781285869759
Author: Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres
Publisher: Cengage Learning
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Chapter 19, Problem 19.25P
Interpretation Introduction

(a)

Interpretation:

The β -lactam portion of amoxicillin and cephalexin is to be identified.

Concept Introduction:

The cyclic amides are known as lactums. The four membered ring containing amide group is known as β -lactam. Amoxicillin is a type of penicillin. The common feature in all penicillin is the β -lactam ring is bonded to the five-membered ring containing sulfur atom. Cephalexin is effective β -lactam antibiotic.

Interpretation Introduction

(b)

Interpretation:

The structural formula of the molecule which is formed by the enzyme catalyzed hydrolysis of the β -lactam ring of penicillin G is to be drawn.

Concept Introduction:

The cyclic amides are known as lactums. The four membered ring containing amide group is known as β -lactam. Due to the presence of β -lactam ring the penicillin G shows antibacterial activity.

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Part II. two unbranched ketone have molecular formulla (C8H100). El-ms showed that both of them have a molecular ion peak at m/2 =128. However ketone (A) has a fragment peak at m/2 = 99 and 72 while ketone (B) snowed a fragment peak at m/2 = 113 and 58. 9) Propose the most plausible structures for both ketones b) Explain how you arrived at your conclusion by drawing the Structures of the distinguishing fragments for each ketone, including their fragmentation mechanisms.
Part V. Draw the structure of compound tecla using the IR spectrum Cobtained from the compound in KBr pellet) and the mass spectrum as shown below. The mass spectrum of compound Tesla showed strong mt peak at 71. TRANSMITTANCE LOD Relative Intensity 100 MS-NW-1539 40 20 80 T 44 55 10 15 20 25 30 35 40 45 50 55 60 65 70 75 m/z D 4000 3000 2000 1500 1000 500 HAVENUMBERI-11
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