Concept explainers
(a)
Interpretation:
The
Concept Introduction:
The cyclic amides are known as lactums. The four membered ring containing amide group is known as
(b)
Interpretation:
The structural formula of the molecule which is formed by the enzyme catalyzed hydrolysis of the
Concept Introduction:
The cyclic amides are known as lactums. The four membered ring containing amide group is known as
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Introduction to General, Organic and Biochemistry
- Cystine is an amino acid formed from the oxidation of twocysteine molecules to form a disulfide bond. The molecular formula of cystine is C6H12O4N2S2. Draw the structural formula of cystine. (arrow_forwardGiven that C6H11COOH has a pKa = 4.8 and C6H11N+H3 has a pKa = 10.7, (a) What pH would you make the water layer to cause the carboxylic acid to dissolve in the water layer and the amine to dissolve in the ether layer? (b) What pH would you make the water layer to cause the carboxylic acid to dissolve in the ether layer and the amine to dissolve in the water layer?arrow_forwardChoose among these options Among these Inhibits the enzyme which is responsible for the assembly of matured viral particles Saquinavir Didanosine Penciclovir Azidothymidine The following are essential components in the structure of sulfonamides with the exception of Amino group Benzene ring Pyridine N-Acyl amino This drug has been associated with optic neuritis and therefore discontinued after 2 months of treatment Isonizaid Rifampicin Ethambutol Pyrazinamide A non prodrug ACE Inhibitor Captopril Enalapril Quinapril Fosinopril High sodium diet High fat diet Low potassium diet Low phosphate dietarrow_forward
- 27. Which of the following statements about cholesterol is not correct? CH3 CH3 H. d но Cholesterol (a) Cholesterol is a steroid that contains a tetracyclic ring system. (b) Cholesterol is a steroid that contains 8 chiral carbons and can form 28 or 256 stereoisomers. (c) Each atom or group attached to a ring-junction carbon (i.e., carbons a -e) is in a trans or axial position. Because of this the tetracyclic ring system is mostly flat. (d) Cholesterol is used to synthesized vitamin D, bile acids, sex hormones, and adrenocorticoid hormones. (e) Cholesterol is not found in the cell membranes of animals.arrow_forward(i)What class of drug is Ranitidine? (ii)If water contains dissolved Ca2+ ions, out of soaps and synthetic detergents, which will you use for cleaning clothes? (iii)Which of the following is an antiseptic? 0.2% phenol, 1% phenolarrow_forwardIndinavir (trade name Crixivan) is a drug used to treat HIV. (a) At which sites can indinavir hydrogen bond to another molecule like itself? (b) At which sites can indinavir hydrogen bond to water?arrow_forward
- 1. Draw structures corresponding to the following IUPAC names: (a) 4-Methylpentanoic acid (b) o-Hydroxybenzoic acid (c) 2,2-Dimethylpropanoyl chloride (d) trans-2-Methylcyclohexanecarboxamide (e) p-Methylbenzoic anhydride (f) p-Bromobenzonitrilearrow_forward(a) Give the omega designation for the following fatty acid: Но (b) Give the omega designation for the following fatty acid: HOarrow_forwardSeveral compounds have been found to inhibit -lactamase, and drugs based on these compounds can be taken in combination with penicillins and cephalosporins to restore their effectiveness when resistance is known to be a problem. The commonly prescribed formulation called Augmentin is a combination of the -lactamase inhibitor shown below with amoxicillin (shown above). It is used to treat childhood ear infections when resistance is suspected, and many kids know it as the white liquid that tastes like bananas. Which of the statements below are true statements? 1. The stereochemistry of the fusion between the four-and five-membered rings in the inhibitor and amoxicillin are different. 2. The inhibitor possesses enol ether and allylic alcohol functional groups while the antibiotic possesses a phenol and a secondary amide functional group. 3. Neither the inhibitor nor the antibiotic contains strained rings. 4. Both 1 and 2 are true.arrow_forward
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