In a molecule of taurocholic acid, the number of attachments to the steroid nucleus has to be predicted. Concept introduction: There are two types of bile acids: simple and complexed. When a small amino group is attached to the carboxyl group of side chain present at carbon 17 through an amide linkage, then the free bile acids get converted into more complex bile acid.
In a molecule of taurocholic acid, the number of attachments to the steroid nucleus has to be predicted. Concept introduction: There are two types of bile acids: simple and complexed. When a small amino group is attached to the carboxyl group of side chain present at carbon 17 through an amide linkage, then the free bile acids get converted into more complex bile acid.
Solution Summary: The author explains that a molecule of taurocholic acid has 6 attachments to the steroid nucleus.
Definition Definition Group of atoms that shape the chemical characteristics of a molecule. The behavior of a functional group is uniform in undergoing comparable chemical reactions, regardless of the other constituents of the molecule. Functional groups aid in the classification and anticipation of reactivity of organic molecules.
Chapter 19, Problem 19.122EP
(a)
Interpretation Introduction
Interpretation: In a molecule of taurocholic acid, the number of attachments to the steroid nucleus has to be predicted.
Concept introduction: There are two types of bile acids: simple and complexed. When a small amino group is attached to the carboxyl group of side chain present at carbon 17 through an amide linkage, then the free bile acids get converted into more complex bile acid.
(b)
Interpretation Introduction
Interpretation: In a molecule of taurocholic acid, the number of different functional groups has to be predicted.
Concept introduction: There are two types of bile acids: simple and complexed. When a small amino group is attached to the carboxyl group of side chain present at carbon 17 through an amide linkage, then the free bile acids get converted into more complex bile acid.
(c)
Interpretation Introduction
Interpretation: In a molecule of taurocholic acid, the number of different functional groups has to be predicted.
Concept introduction: There are two types of bile acids: simple and complexed. When a small amino group is attached to the carboxyl group of side chain present at carbon 17 through an amide linkage, then the free bile acids get converted into more complex bile acid.
(d)
Interpretation Introduction
Interpretation: In a molecule of taurocholic acid, the number of different elements has to be predicted.
Concept introduction: There are two types of bile acids: simple and complexed. When a small amino group is attached to the carboxyl group of side chain present at carbon 17 through an amide linkage, then the free bile acids get converted into more complex bile acid.
3.
a.
Use the MS to propose at least two possible molecular formulas.
For an unknown compound:
101.
27.0
29.0
41.0
50.0
52.0
55.0
57.0
100
57.5
58.0
58.5
62.0
63.0
64.0
65.0
74.0
40
75.0
76.0
20
20
40
60
80
100
120
140
160
180
200 220
m/z
99.5
68564810898409581251883040
115.0
116.0
77404799
17417M
117.0
12.9
118.0
33.5
119.0
36
133 0
1.2
157.0
2.1
159.0
16
169.0
219
170.0
17
171.0
21.6
172.0
17
181.0
1.3
183.0
197.0
100.0
198.0
200.
784
Relative Intensity
2
2
8
ō (ppm)
6
2
Solve the structure and assign each of the following spectra (IR and C-NMR)
1.
For an unknown compound with a molecular formula of C8H100:
a.
What is the DU? (show your work)
b.
Solve the structure and assign each of the following spectra.
8
6
2
ō (ppm)
4
2
0
200
150
100
50
ō (ppm)
LOD
D
4000
3000
2000
1500
1000
500
HAVENUMBERI -11
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