Bundle: Chemistry for Today: General, Organic, and Biochemistry, Loose-Leaf Version, 9th + LMS Integrated OWLv2, 4 terms (24 months) Printed Access Card
9th Edition
ISBN: 9781337598255
Author: Spencer L. Seager
Publisher: Cengage Learning
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Textbook Question
Chapter 15, Problem 15.16E
List the following compounds in order of increasing water solubility:
a. ethoxyethane
b. propanoic acid
c. pentane
d.
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Learning Goal:
As discussed during the lecture, the enzyme HIV-1 reverse transcriptae (HIV-RT) plays a significant role for the HIV virus and is an important drug target. Assume a concentration [E] of 2.00 µM (i.e. 2.00 x 10-6 mol/l) for HIV-RT. Two potential drug molecules, D1 and D2, were identified, which form stable complexes with the HIV-RT.
The dissociation constant of the complex ED1 formed by HIV-RT and the drug D1 is 1.00 nM (i.e. 1.00 x 10-9). The dissociation constant of the complex ED2 formed by HIV-RT and the drug D2 is 100 nM (i.e. 1.00 x 10-7).
Part A - Difference in binding free eenergies
Compute the difference in binding free energy (at a physiological temperature T=310 K) for the complexes. Provide the difference as a positive numerical expression with three significant figures in kJ/mol.
The margin of error is 2%.
Part B - Compare difference in free energy to the thermal energy
Divide the…
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Chapter 15 Solutions
Bundle: Chemistry for Today: General, Organic, and Biochemistry, Loose-Leaf Version, 9th + LMS Integrated OWLv2, 4 terms (24 months) Printed Access Card
Ch. 15 - Prob. 15.1ECh. 15 - Prob. 15.2ECh. 15 - Prob. 15.3ECh. 15 - What carboxylic acid is present in sour milk and...Ch. 15 - Write the correct IUPAC name for each of the...Ch. 15 - Write the correct IUPAC name for each of the...Ch. 15 - Prob. 15.7ECh. 15 - Prob. 15.8ECh. 15 - Prob. 15.9ECh. 15 - Prob. 15.10E
Ch. 15 - Prob. 15.11ECh. 15 - Prob. 15.12ECh. 15 - Prob. 15.13ECh. 15 - Caproic acid, a six-carbon acid, has a solubility...Ch. 15 - Why are acetic acid, sodium acetate, and sodium...Ch. 15 - List the following compounds in order of...Ch. 15 - Prob. 15.17ECh. 15 - Prob. 15.18ECh. 15 - Prob. 15.19ECh. 15 - Prob. 15.20ECh. 15 - Write an equation to illustrate the equilibrium...Ch. 15 - Prob. 15.22ECh. 15 - Complete each of the following reactions: a. b.Ch. 15 - Prob. 15.24ECh. 15 - Write a balanced reaction for the reaction of...Ch. 15 - Prob. 15.26ECh. 15 - Give the IUPAC name for each of the following: a....Ch. 15 - Prob. 15.28ECh. 15 - Prob. 15.29ECh. 15 - Prob. 15.30ECh. 15 - Prob. 15.31ECh. 15 - Give the name of a carboxylic acid or carboxylate...Ch. 15 - Prob. 15.33ECh. 15 - Prob. 15.34ECh. 15 - Complete the following reactions: a. b. c.Ch. 15 - Prob. 15.36ECh. 15 - Using the alcohol CH3CH2OH, show three different...Ch. 15 - Prob. 15.38ECh. 15 - Prob. 15.39ECh. 15 - Prob. 15.40ECh. 15 - Prob. 15.41ECh. 15 - Prob. 15.42ECh. 15 - Prob. 15.43ECh. 15 - Prob. 15.44ECh. 15 - Give the IUPAC name for each of the following: a....Ch. 15 - Prob. 15.46ECh. 15 - Prob. 15.47ECh. 15 - Prob. 15.48ECh. 15 - Prob. 15.49ECh. 15 - Prob. 15.50ECh. 15 - Prob. 15.51ECh. 15 - Prob. 15.52ECh. 15 - Complete the following reactions: a. b.Ch. 15 - Prob. 15.54ECh. 15 - Prob. 15.55ECh. 15 - Dihydroxyacetone reacts with phosphoric acid to...Ch. 15 - Prob. 15.57ECh. 15 - Prob. 15.58ECh. 15 - Prob. 15.59ECh. 15 - Prob. 15.60ECh. 15 - How many mL of a 0.100M NaOH solution would be...Ch. 15 - Prob. 15.62ECh. 15 - Prob. 15.63ECh. 15 - Prob. 15.64ECh. 15 - Prob. 15.65ECh. 15 - Prob. 15.66ECh. 15 - Prob. 15.67ECh. 15 - Why is it safe for us to consume foods like...Ch. 15 - Prob. 15.69ECh. 15 - Prob. 15.70ECh. 15 - Prob. 15.71ECh. 15 - Prob. 15.72ECh. 15 - Identify the functional group designated by each...Ch. 15 - Prob. 15.74ECh. 15 - Fats belong to the class of organic compounds...
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