Aspirin from Wintergreen:1. In isolating the salicylic acid, why is it important to press out as much of the water as possible?Write a step-by-step mechanism for the esterification of salicylic acid with acetic anhydride catalyzed by concentrated H₂SO4.3. Calculate the exact monoisotopic mass of aspirin showing your work.What signals appeared/disappeared/shifted that indicate that you have your intended product and not starting material? Whatother impurities are present in your product and how do you know?

2. Write a step-by-step mechanism for the esterification of salicylic acid with acetic anhydride…

Answered: Aspirin from Wintergreen: 1. In…

EBK A SMALL SCALE APPROACH TO ORGANIC L

4th Edition

ISBN:9781305446021

Author:Lampman

Publisher:Lampman

Chapter84: Fractional Distillation, Azeotropes

Section: Chapter Questions

Problem 8P

See similar textbooks

Similar questions

In Part A, the mass of KHC,H,O, is measured to the nearest 0.0001 g. However, the volume of water used to dissolve the KHP does not need to be precise. Explain why the amount of water added to KHP has no effect on the experimental results.
A student prepared 2-butanone (C4H&O) in the lab. To determine the purity of the product, the ketone was reacted with excess hydroxylamine hydrochloride liberating HCI. In this study, as much as 3.00 ml of sample was diluted to 50 mL and was treated with an excess of hydroxylamine hydrochloride. The liberated HCI was then titrated with 0.9989 M NaOH, requiring 32.68 mL to reach the end point. 1. Show how 2-butanone can be prepared! 2. Determine the percent purity of the sample, given that the density of 2-butanone is 0.805 g/mL!
You prepare a buffer solution from 10.0 mL of 0.100M MOPS (3‑morpholinopropane‑1‑sulfonic acid) and 10.0 mL of 0.075 M NaOH. Next, you add 1.00 mL of 4.15×10−4 M lidocaine to this mixture. Denoting lidocaine as L, calculate the fraction of lidocaine present in the form LH+. MOPS Ka = 6.3 * 10^-8 Lidocaine Kb = 8.7 * 10^-7 ( Please type answer note write by hend )
An unknown sample containing mixed alkali (NAOH, NaHCO3, or NazCO3) was analyzed using the double flask method. A 250 mg sample was dissolved in 250 mL CO, free water. A 20.0 mL aliquot of this sample required 11.3 mL of 0.009125 M HCI solution to reach the phenolphthalein end point. Another 29.0 mL aliquot of the sample was titrated to the bromocresol green endpoint using 311 mL of the standard acid. What is/are the component/s of the sample? O Cannot be determined O NAHCO3 only O NAOH and Na,CO3 O NazCO3 only O NAHCO, and Na2CO3
4-bromobenzoic acid (1.0 g) is dissolved in 20 ml dichloromethane. After addition to a separatory funnel, the dichloromethane solution is treated with 20 ml 3.0 M NaOH solution. After the layers are separated, which layer(s) will contain an organic compound (non-solvent)? What would happen if the aqueous layer is treated with 20 ml 3.0 M HCl?
a) When considering the overall dialysis procedure, why is it important to exchange old/used dialysis buffer (or “dialysate” solution) with a fresh dialysis buffer solution at least once throughout the process? NOTE: Your TAs will do this for your group’s samples over the next week. b) This week’s lab utilizes a dialysis buffer with the following composition: 10 mM Tris-HCl, 10 mM MgSO4, and a pH of 7.4. Let’s presume an ERROR occurred with the creation of this buffer during the pH titration and you unknowingly titrated to a final pH of 5.0. What effects, if any, could you expect to observe on your final, dialyzed sample?
Explain the role of phenolphthalein in the standardization of NaOH with KHP
Standard solution : 0.201 grams of acetylsalicylic acid was combined with 10 mL of 0.5 M NaOH, then transfered to a 100 mL flask and filled the rest of the way with water Then 0.500 mLs of the standard solution was transfered to a 10.00 mL flask and diluted to the 10 mL mark with 0.02 M of buffered iron chloride. Number of moles of NaOH = 0.005 moles Since the reaction between acetylsalicylic acid and NaOH is a 1:1 reaction, the number of moles of acetylsalicylic acid used in the reaction is also 0.005 moles. the concentration from analysis question 5: acetylsalicylic acid in the 100.00 mL volumetric flask is 0.050 M. From your plot, what is the value of εb? From the Beer- Lambert law For the aspirin sample, calculate the concentration of acetylsalicylic acid present using the value of εb that you found The concentration from analysis question 5 represents the concentration in the 10.00 mL sample that was prepared in the volumetric flask using an aliquot of the solution in the…
5. If the concentrated phosphoric acid (H3PO4) is 15.2 M, determine the molar ratio of H3PO4 to cyclohexanol, if one used 9.13 g of cyclohexanol and 4.0 mL of H3PO4. Show your calculations. Was cyclohexanol or H3PO4 the limiting reagent? Briefly explain.
Twenty sodium salicylate tablets labeled 325 mg were dispersed in sufficient water to make 200.0 ml. A 15.0-ml aliquot of the filtrate was titrated to a bromophenol blue end point in the usual way by 29.11 ml of 0.1000 N hydrochloric acid. Calculate the amount of sodium salicylate in each tablet and, from that, the percentage of the labeled amount. Hint: Use the above formula.
You prepare a buffer solution from 10.0 mL of 0.100 M MOPS (3-morpholinopropane-1-sulfonic acid) and 10.0 mL of 0.084 M NaOH. Next, you add 1.00 mL of 7.87 x 10-4 M lidocaine to this mixture. Denoting lidocaine as L, calculate the fraction of lidocaine МOPS present in the form LH*. K, = 6.3 x 10-8 CH3 NH fraction as LH* : CH3 Lidocaine K, = 8.7 x 10-7
Explain why different results are observed when HCl and H2SO4 are added to brine?

SEE MORE QUESTIONS

Recommended textbooks for you

EBK A SMALL SCALE APPROACH TO ORGANIC L

Chemistry

ISBN:

9781305446021

Author:

Lampman

Publisher:

CENGAGE LEARNING - CONSIGNMENT

EBK A SMALL SCALE APPROACH TO ORGANIC L

Chemistry

ISBN:

9781305446021

Author:

Lampman

Publisher:

CENGAGE LEARNING - CONSIGNMENT

SEE MORE TEXTBOOKS