Chapter 11, Problem 32RA

Summary Introduction

To review:

1.The differences between steroid and non-steroid group of nuclear hormone receptors.

2. The role of vitamin A in the actions of the non-steroid group of receptors.

Introduction:

The nuclear hormone receptors are categorized under the family of transcription factors that employ both positive as well as negative regulation of the gene expression. These participate in the developmental, survival and hormonal functions. The discovery of first nuclear hormone receptor was done during the defining of the mechanism of action of several hormones and vitamins.