Interpretation:The reason behind much higher yield of
Concept introduction:
The product formed is governed by Markovnikov’s Rule. Rule suggests that negative part of halo acid HX must go to the carbon that has more alkyl substituents or less
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Experimental Organic Chemistry: A Miniscale & Microscale Approach (Cengage Learning Laboratory Series for Organic Chemistry)
- Possible alternative brominations include: Veratrole (1,2-dimethoxybenzene) to 1,2-dibromo-4,5-dimethoxybenzene; 4-Methylacetanilide to 2-bromo-4-methylacetanilide; 2-Methylacetanilide (made in experiment S.1) to 4-bromo-2-methylacetanilide; Vanillin to 5-bromovanillin; Acetanilide to 4-bromoacetanilide; a. b. C. d. e. EXPERIMENT S4: BROMINATION OF AROMATIC COMPOUNDS Certain other acetanilides made in experiment S.1 may also be used as precursors in this experiment. Estimated time: 1 afternoon Associated learning goals: Section 6, LG 6.6; Section 7, LG 7.2 and 7.4 Pre-lab report: complete the standard report form, and answer the following questions. In this experiment, molecular bromine (Br2) is generated from the redox reaction of potassium bromate with hydrobromic acid. Write a balanced equation for this process. Briefly outline the mechanism by which Br2 brominates your aromatic compound. Why do the bromine atoms end up at the positions indicated rather than anywhere else in the…arrow_forwardFor the following reaction scheme, match the correct reagent to each reaction (A, B, C, D and E).arrow_forwardA 1-butene reacts with can yield butan-1,2-diol when it reacts with potassium permanganate in a basic medium. True or Falsearrow_forward
- Which compound is the major product of the reaction below? QH (1) LIAIH,/ether N. N. N. (2) H* (dil.)/H,O (A) (B) HO, (C) (D) O Compound B O Compound A Compound C Compound Darrow_forward1. Which compound is expected to have a higher melting point, 1-pentanol or 1-pentanal? Explain 2. Which compound is expected to be more soluble in water, propanal or butanal? Explain. 3. Why is acetyl chloride more reactive towards hydrolysis than ethyl acetate?arrow_forwardIdentify the reagents that to perform the following reactionarrow_forward
- What alkene is needed to synthesize the following 1,2-diol using the given reagents? Be sure to answer all parts. CH3CH₂CH2 [1] OsO4 followed by NaHSO3 in H₂O: [2] CH3CO3H followed by "OH in H₂O: H OH OH CH₂CH₂CH3 draw structure... draw structure ...arrow_forwardComplete the following reaction scheme. 1. DIBALH 2. H3O+ TMSCI Pyridine 1. LIAIH(t-BuO)3 SOCI2 2. H3O+ CrO3 H3O+arrow_forward.0. For 0.1 M equimolar reaction of CH3COOH + NH3 ----> CH3-CO-O™ + NH4+ How does the concentration of ]? [CH3COOH] compare to that of [CH3-CO-O (a) Equal (b) Greater than (c) Less than) (d) not possible determine aarrow_forward
- Does doubling the concentration of an alkylhalide and maintaining the alkoxide concentration double the reaction rate? What if the alkylhalide concentration is maintained and the alkoxide concentration is doubled?arrow_forwardWhy is the reaction more favorable at lower pH?arrow_forwardthe most stable intermediatearrow_forward
- Organic Chemistry: A Guided InquiryChemistryISBN:9780618974122Author:Andrei StraumanisPublisher:Cengage LearningOrganic ChemistryChemistryISBN:9781305580350Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. FootePublisher:Cengage Learning