Skeletal muscle myosin heavy chain is a mechanoenzyme that requires ATP for its function. Other enzymes, such as phosphofructokinase-2, also rely on ATP. How are PFK-2 and myosin Il different in their use of ATP? • View Available Hint(s) Both enzymes use ATP in the exact same way. PFK-2 functions as a kinase, whereas myosin functions as a phosphatase. O PFK-2 catalyzes ATP hydrolysis, whereas myosin does not. Myosin catalyzes ATP hydrolysis, whereas PFK-2 does not. O PFK-2 binds to ATP or ADP + Pj, whereas myosin undergoes covalent modification via phosphorylation. O O O O O

Human Physiology: From Cells to Systems (MindTap Course List)
9th Edition
ISBN:9781285866932
Author:Lauralee Sherwood
Publisher:Lauralee Sherwood
Chapter8: Muscle Physiology
Section: Chapter Questions
Problem 2TAHL
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**Question:**

Skeletal muscle myosin heavy chain is a mechanoenzyme that requires ATP for its function. Other enzymes, such as phosphofructokinase-2, also rely on ATP. How are PFK-2 and myosin II different in their use of ATP?

**Options:**

- Both enzymes use ATP in the exact same way.

- PFK-2 functions as a kinase, whereas myosin functions as a phosphatase.

- PFK-2 catalyzes ATP hydrolysis, whereas myosin does not.

- Myosin catalyzes ATP hydrolysis, whereas PFK-2 does not.

- PFK-2 binds to ATP or ADP + Pi, whereas myosin undergoes covalent modification via phosphorylation.

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Transcribed Image Text:**Question:** Skeletal muscle myosin heavy chain is a mechanoenzyme that requires ATP for its function. Other enzymes, such as phosphofructokinase-2, also rely on ATP. How are PFK-2 and myosin II different in their use of ATP? **Options:** - Both enzymes use ATP in the exact same way. - PFK-2 functions as a kinase, whereas myosin functions as a phosphatase. - PFK-2 catalyzes ATP hydrolysis, whereas myosin does not. - Myosin catalyzes ATP hydrolysis, whereas PFK-2 does not. - PFK-2 binds to ATP or ADP + Pi, whereas myosin undergoes covalent modification via phosphorylation. **Submit Button:** Below the options, there is a "Submit" button to finalize your selection.
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