Choose a FALSE statement about Hill's plot. All or none binding is given by n = N² (N is the total number of binding sites, n is the number of sites where ligand is fully bound). Hill coefficient can be non-integer O The ends of the curve in Hill's plot can not have slopes greater than unity because they correspond to binding of the first and last ligand molecule to the macromolecule. O when there is no cooperativity n = 1
Choose a FALSE statement about Hill's plot. All or none binding is given by n = N² (N is the total number of binding sites, n is the number of sites where ligand is fully bound). Hill coefficient can be non-integer O The ends of the curve in Hill's plot can not have slopes greater than unity because they correspond to binding of the first and last ligand molecule to the macromolecule. O when there is no cooperativity n = 1
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
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Please I don’t understand this Biochem question. An explanation leading to both of the CORRECT answers would be helpful!

Transcribed Image Text:Choose a FALSE statement about Hill's plot.
All or none binding is given by n = N² (N is the total number of binding sites, n is the number of sites where
ligand is fully bound).
Hill coefficient can be non-integer
O The ends of the curve in Hill's plot can not have slopes greater than unity because they correspond to
binding of the first and last ligand molecule to the macromolecule.
O when there is no cooperativity n = 1

Transcribed Image Text:Choose a FALSE statement about hemoglobin
has four subunits
OT to R transition results in narrowing of the pocket between the ß subunits
Hill coefficient is n=3
T and R states are in equilibrium. Binding ligand shifts the equilibrium toward R state.
is a tetramer with subunits similar in structure to myoglobin
O individual subunits has cooperativity coefficient n>1
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