Please answer with lots of explanation. It is not a pharmacology question. It is an estimation problem based off of pharmacology. 6) * Earlier this semester (in the Class 1 Handout Practice Problems), we learned thatindividuals with an HIV infection are typically treated with a combination of three or moredrugs – commonly known as HAART (highly active antiretroviral therapy) – to suppressviral replication. We also learned that one of the drugs included in HAART isazidothymidine (AZT), which inhibits HIV's ability to convert its single-stranded RNAgenome into double-stranded DNA, and we calculated that the concentration of AZT in a|typical patient's bloodstream is 90 µg/mL. Given that AZT's molecular formula isC10H13N5O4, and given that an average human adult has ~5 L of blood in their body howmany molecules of AZT are in a typical patient's body?

Answered: 6) * Earlier this semester (in the…

Phlebotomy Essentials

6th Edition

ISBN:9781451194524

Author:Ruth McCall, Cathee M. Tankersley MT(ASCP)

Publisher:Ruth McCall, Cathee M. Tankersley MT(ASCP)

Chapter1: Phlebotomy: Past And Present And The Healthcare Setting

Section: Chapter Questions

Problem 1SRQ

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Question

Please answer with lots of explanation. It is not a pharmacology question. It is an estimation problem based off of pharmacology.

6) * Earlier this semester (in the Class 1 Handout Practice Problems), we learned that
individuals with an HIV infection are typically treated with a combination of three or more
drugs – commonly known as HAART (highly active antiretroviral therapy) – to suppress
viral replication. We also learned that one of the drugs included in HAART is
azidothymidine (AZT), which inhibits HIV's ability to convert its single-stranded RNA
genome into double-stranded DNA, and we calculated that the concentration of AZT in a
|
typical patient's bloodstream is 90 µg/mL. Given that AZT's molecular formula is
C10H13N5O4, and given that an average human adult has ~5 L of blood in their body how
many molecules of AZT are in a typical patient's body?

Expert Solution

Step 1

The body's immune system is in charge of warding off infection. It accomplishes this in a variety of methods, including physical and chemical barriers as well as cells. However, HIV (human immunodeficiency virus) is a virus that affects immune cells and can be transmitted from one person to another by certain bodily fluids. As a result, the body becomes more susceptible to other infections and diseases. If HIV is not treated, it can progress to AIDS (acquired immunodeficiency syndrome).

Azidothymidine (AZT) is another name for zidovudine (ZDV). It is an antiretroviral medication for patients with HIV/AIDS. AZT is usually given twice a day in combination with other antiretroviral drugs.